醋丁洛尔对眼部、全身及抗核抗体的影响
Ocular, systemic and antinuclear antibody changes with acebutolol.
作者信息
Hosie J, Ghafoor S Y
出版信息
J R Coll Gen Pract. 1983 Dec;33(257):779-82.
Abstract
A group of 29 hypertensive patients were studied for side effects of acebutolol. An antinuclear antibody titre of >/=1/64 developed in 23 per cent of patients during a 12-month course of treatment. Full ophthalmic examination before and after the treatment period showed a statistically significant increase in tear secretion at one year. One patient had a slight worsening of her psoriasis. No patients developed any symptoms or signs of oculomucocutaneous syndrome (OMCS) or systemic lupus erythematosus (SLE).
摘要
对一组29名高血压患者进行了醋丁洛尔副作用的研究。在为期12个月的治疗过程中，23%的患者抗核抗体滴度≥1/64。治疗前后的全面眼科检查显示，一年时泪液分泌有统计学意义的增加。一名患者的牛皮癣略有恶化。没有患者出现任何眼黏膜皮肤综合征（OMCS）或系统性红斑狼疮（SLE）的症状或体征。
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