Blumberg N, Masel D, Mayer T, Horan P, Heal J
Blood. 1984 Feb;63(2):448-50.
Recent evidence suggests that HLA-A,B antigens present on human platelets, are acquired from plasma. Using hypertonic acid chloroquine (200 mg/ml, pH 5.0, 1 hr, 4 degrees C), we demonstrate elution of most or all HLA-A2 and HLA-B7,40 immunoreactive material from platelets. Corresponding antigens on human lymphocytes were not affected by this treatment. These findings are consistent with the hypothesis that HLA-A,B antigens are adsorbed onto platelet surfaces.
最近有证据表明，人类血小板上存在的HLA - A、B抗原是从血浆中获得的。使用高渗酸性氯喹（200毫克/毫升，pH值5.0，1小时，4℃），我们证明了大多数或所有HLA - A2和HLA - B7、40免疫反应性物质从血小板上洗脱。人类淋巴细胞上的相应抗原不受该处理的影响。这些发现与HLA - A、B抗原吸附在血小板表面的假说一致。
