Research on heterocyclic compounds. XV. Substitution influence on the pharmacological activity in a series of imidazo[1,2-a]pyridines.
作者信息
Abignente E, Arena F, Avara P, Biniecka M, Luraschi E, Marmo E, Cazzola M, Filippelli W
出版信息
Farmaco Sci. 1983 Dec;38(12):911-28.
PMID:6607848
Abstract
We have taken into consideration a group of 28 imidazo [1,2-a]pyridine derivatives, some of which were already known, whereas the others have been synthesized and characterized to complete the series. Antiinflammatory, analgesic, antipyretic and ulcerogenic activities of such compounds were evaluated in comparison with indomethacin. The pharmacological data demonstrated the effects exerted on activity by the presence on the heterocyclic system of methyl substituents and/or an acidic moiety.
摘要
相似文献
1
Research on heterocyclic compounds. XV. Substitution influence on the pharmacological activity in a series of imidazo[1,2-a]pyridines.
Farmaco Sci. 1983 Dec;38(12):911-28.
2
Research on heterocyclic compounds. XXII. Imidazo[1,2-a]pyrimidines.
Farmaco Sci. 1987 Sep;42(9):657-69.
3
Research on heterocyclic compounds. XIX--2-Methylimidazo[1,2-a]pyridine-3-acetic acids.
Farmaco Sci. 1986 Feb;41(2):119-30.
4
Research on heterocyclic compounds. XXVIII. Imidazo[1,2-c]pyrimidines.
Farmaco. 1991 Oct;46(10):1099-110.
5
6
Research on heterocyclic compounds. IX - Heteroarylcarboxamides and acetamides: antiinflammatory and related pharmacological properties.
Farmaco Sci. 1980 Aug;35(8):654-73.
7
Research on heterocyclic compounds. X.-Imidazo[1,2-a]pyrazine derivatives: synthesis and antiinflammatory activity.
Farmaco Sci. 1981 Jan;36(1):61-80.
8
9
10
Research on heterocyclic compounds. XXIV. Antiinflammatory activity of some imidazo[1,2-c]pyrimidine derivatives.
Res Commun Chem Pathol Pharmacol. 1988 Aug;61(2):167-83.
Zotero 插件