Saku K, Sugimoto K, Uchiyama Y
Jpn J Antibiot. 1983 Oct;36(10):2757-62.
Using 3 kinds of medium, Mueller-Hinton (M-H) agar, M-H agar added with defibrinated horse blood and lysed horse blood, susceptibilities of Campylobacter were tested quantitatively to 12 antibacterial agents. The result showed no remarkable difference between them. MIC was examined with the cell concentration of McFarland unit 0.5 and 100-times dilution, and there was no significant difference between them except for 2 strains, on which erythromycin showed MIC of 6.25 micrograms/ml at McFarland unit 0.5 and 0.39 micrograms/ml at 100-times dilution. Eighty-two clinical isolates of C. jejuni and 6 of C. coli were tested for their susceptibility to 12 antibacterial agents. These strains were most susceptible to gentamicin and amikacin and less susceptible to benzylpenicillin, carbenicillin and cephaloridine with the MIC of 25 micrograms/ml. There were 2 peaks of susceptibility distribution to minocycline (0.2 and 50 micrograms/ml). In tests for beta-lactamase of C. jejuni and C. coli, 3 strains obtained from 1 patient were positive.
使用3种培养基,即穆勒-欣顿(M-H)琼脂、添加去纤维马血的M-H琼脂和溶血马血的M-H琼脂,对弯曲杆菌进行了12种抗菌剂的定量药敏试验。结果显示它们之间无显著差异。以麦氏单位0.5的菌液浓度和100倍稀释液检测最低抑菌浓度(MIC),除2株菌株外,它们之间无显著差异,这2株菌株在麦氏单位0.5时红霉素的MIC为6.25微克/毫升,在100倍稀释时为0.39微克/毫升。对82株空肠弯曲菌临床分离株和6株结肠弯曲菌临床分离株进行了12种抗菌剂的药敏试验。这些菌株对庆大霉素和阿米卡星最敏感,对苄青霉素、羧苄青霉素和头孢菌素的敏感性较低,MIC为25微克/毫升。对米诺环素的药敏分布有2个峰值(0.2和50微克/毫升)。在对空肠弯曲菌和结肠弯曲菌的β-内酰胺酶检测中,从1例患者中分离出的3株菌株呈阳性。