光胆红素II的白蛋白结合
Albumin binding of photobilirubin II.
作者信息
Meisel P, Biebler K E, Gens A, Jaehrig K
出版信息
Biochem J. 1983 Jul 1;213(1):25-9. doi: 10.1042/bj2130025.
Abstract
Photobilirubin II, a stereoisomer of bilirubin, binds to human serum albumin at a single binding site (K = 2.2 x 10(6)M-1), presumably the high-affinity bilirubin-binding site. Binding in the secondary (class II) binding sites is of minor importance. The results are discussed with respect to photometabolism of bilirubin and as a possible source of error in the determination of bilirubin unbound to albumin.
摘要
光胆红素II是胆红素的一种立体异构体，它在单个结合位点与人血清白蛋白结合（K = 2.2×10⁶M⁻¹），该位点可能是高亲和力胆红素结合位点。在二级（II类）结合位点的结合重要性较低。就胆红素的光代谢以及作为未与白蛋白结合胆红素测定中可能的误差来源对结果进行了讨论。
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