Yamaguchi K, Schoefl G I
Anat Rec. 1983 Aug;206(4):391-401. doi: 10.1002/ar.1092060406.
The topographic distribution of blood vessels in Peyer's patches of mice was studied by light and scanning electron microscopy with whole mounts of flattened gut segments and vascular corrosion casts. Peyer's patches are imbedded in the intestinal wall and share its blood supply. Two to four mural trunks may contribute to the area of the patch. In and around the lymphoid nodules the microcirculation is highly specialized. The nodule is permeated by a meshwork of fine capillaries that is supplied by arterioles entering on the serosal and lateral surfaces. Blood flow to the lymphoid nodule appears to be monitored by arterial sphincters; the dense lymphatic tissue can also be bypassed by arteriovenous communications. An extensive venous network encircles the nodule. Most of these venules are lined by high endothelium which is penetrated by lymphocytes. The geometry of these vessels suggests a slow and turbulent flow in these vascular segments that may aid margination of lymphocytes. A planar capillary plexus lies subjacent to the mucosal epithelium in the dome area.
通过对扁平肠段整装标本和血管铸型进行光镜和扫描电镜观察，研究了小鼠派尔集合淋巴结中血管的拓扑分布。派尔集合淋巴结嵌入肠壁并共享其血液供应。两到四条壁干可能为集合淋巴结区域供血。在淋巴小结及其周围，微循环高度特化。小结被由从浆膜面和侧面进入的小动脉供血的细毛细血管网所贯穿。流向淋巴小结的血流似乎受动脉括约肌监测；致密的淋巴组织也可通过动静脉交通绕过。广泛的静脉网环绕着小结。这些小静脉大多由高内皮细胞衬里，淋巴细胞可穿透该内皮。这些血管的几何结构表明这些血管段内血流缓慢且紊乱，这可能有助于淋巴细胞的边缘化。在圆顶区，一个平面毛细血管丛位于黏膜上皮下方。
