在缺乏卵巢激素的情况下，通过全身或颅内给予前列腺素E2诱导大鼠脊柱前凸。
Lordosis induction in the rat by prostaglandin E2 systemically or intracranially in the absence of ovarian hormones.
作者信息
Rodriguez-Sierra J F, Komisaruk B R
出版信息
Prostaglandins. 1978 Mar;15(3):513-24. doi: 10.1016/0090-6980(78)90135-1.
PMID:663284
Abstract
Within 20 minutes of an intraperitoneal injection, PGE2 induced lordosis responding to manual stimulation in 6 of 9 rats that were ovariectomized-hysterectomized and hormonally untreated. Similarly, intracranial application of PGE2, through guide cannulae that were chronically-implanted in the basal hypothalamus, induced lordosis responding to manual stimulation within 10 minutes in ovariectomized, hormonally-untreated rats.
摘要
腹腔注射后20分钟内，前列腺素E2（PGE2）使9只接受卵巢切除-子宫切除且未进行激素处理的大鼠中的6只对人工刺激产生脊柱前凸反应。同样，通过长期植入下丘脑基部的引导套管向颅内施用PGE2，在卵巢切除且未进行激素处理的大鼠中，10分钟内即引发了对人工刺激的脊柱前凸反应。
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