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脑内前列腺素E2:对去卵巢雌性大鼠性行为、旷场活动及体温的影响

Intracerebral prostaglandin E2: effects upon sexual behavior, open field activity and body temperature in ovariectomized female rats.

作者信息

Hall N R, Luttge W G, Berry R B

出版信息

Prostaglandins. 1975 Nov;10(5):877-88. doi: 10.1016/0090-6980(75)90015-5.

Abstract

A single 27 gauge implant of PGE2 into the periventricular region of the hypothalamus resulted in a significant increase in sexual receptivity in estrogen primed, ovariectomized female rats. Open field activity levels were only slightly decreased while rectal body temperature increased significantly over control values. It is postulated that the effects upon sexual receptivity might be mediated by PGE2 stimulated LRF release.

摘要

在下丘脑室周区域单次植入27号规格的前列腺素E2,可使经雌激素预处理的去卵巢雌性大鼠的性接受能力显著增强。旷场活动水平仅有轻微下降,而直肠体温比对照值显著升高。据推测,对性接受能力的影响可能是由前列腺素E2刺激促黄体释放因子释放介导的。

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