Zaliubovskaia N P, Kiselev R I, Turchaninova L N
Vopr Virusol. 1978 Mar-Apr(2):157-60.
Influenza A2/Victoria virus in the process of development in chick embryos exerted an inhibiting effect on the energy metabolism of liver mitochondria which was manifested in reduced intensity of oxidation and oxidative phosphorylation in mitochondria and increased chemiluminescence of the allantoic fluid. It is assumed that the development of influenza virus is associated with changes in permeability and destruction of membrane structures of the cell leading to the release of lipid complexes and disturbances in electron transport in the respiration chain.
在鸡胚中发育的甲型流感病毒A2/维多利亚株对肝线粒体的能量代谢产生抑制作用,表现为线粒体中氧化及氧化磷酸化强度降低,尿囊液化学发光增强。据推测,流感病毒的发育与细胞通透性的改变及膜结构的破坏有关,这会导致脂质复合物的释放及呼吸链中电子传递的紊乱。