Epstein N E, Epstein J A, Carras R, Lavine L S
Neurosurgery. 1983 Nov;13(5):555-61. doi: 10.1227/00006123-198311000-00012.
The treatment over the past 12 years of 60 patients with degenerative spondylolisthesis with an intact neural arch is reviewed. The patients averaged 65 years of age, with women outnumbering men by a ratio of 2:1. Symptoms in the lower extremities had been present for 3 months to 10 years, although varying back pain had existed for longer periods. Two-thirds showed signs of motor dysfunction. Sensory alterations and a positive Las ègue's sign could be demonstrated in only one-half of the patients studied. Four of 5 patients developed intermittent neurogenic claudication, with varying evidence of painful radiculopathy. The marked disability caused by claudication contrasted sharply with the lesser neurological changes, and these patients required early surgical decompression. Diagnostic studies included electromyography, plain x-ray films, tomography, computed tomographic scanning, and myelography. The latter outlined a relative stenosis caused by olisthesis as well as arthrotic and spondylotic changes that determined the extent of decompressive operation required. The L-4, L-5 interspace was involved in 56 patients, L-3, L-4 was involved in 2, and L-5, S-1 was involved in 2. The ideal operation with L-4, L-5 olisthesis included complete laminectomy of L-4 and L-5 with unroofing of the lateral recesses and foraminotomy. This more extensive procedure was justified because of the failures encountered in previous patients in whom inadequate decompression had been performed. Among failures, obesity, diabetes, hyperlordosis, and extensive long-standing dysfunction were prominent. The relief of symptoms of intermittent neurogenic claudication was the most gratifying response observed. There was no unusual morbidity.
回顾了过去12年中60例神经弓完整的退行性腰椎滑脱患者的治疗情况。患者平均年龄65岁,女性与男性的比例为2:1。下肢症状出现了3个月至10年,尽管不同程度的背痛出现的时间更长。三分之二的患者表现出运动功能障碍的体征。在所研究的患者中,只有一半能表现出感觉改变和阳性直腿抬高试验结果。5例患者中有4例出现间歇性神经源性跛行,并伴有不同程度的疼痛性神经根病的证据。跛行导致的明显残疾与较轻的神经学改变形成鲜明对比,这些患者需要早期手术减压。诊断性检查包括肌电图、普通X线片、体层摄影、计算机断层扫描和脊髓造影。脊髓造影显示了由椎体滑脱以及关节病和脊椎关节强硬性改变引起的相对狭窄,这些改变决定了所需减压手术的范围。56例患者累及L-4、L-5间隙,2例累及L-3、L-4间隙,2例累及L-5、S-1间隙。对于L-4、L-5椎体滑脱的理想手术包括L-4和L-5的全椎板切除术,同时打开侧隐窝和进行椎间孔切开术。由于之前对减压不充分的患者治疗失败,所以采用这种更广泛的手术是合理的。在治疗失败的患者中,肥胖、糖尿病、腰椎前凸过度和广泛的长期功能障碍较为突出。间歇性神经源性跛行症状的缓解是观察到的最令人满意的反应。没有出现异常的并发症。