罂粟碱的代谢IV. 人体中罂粟碱代谢产物的尿排泄情况
Metabolism of papaverine IV. Urinary elimination of papaverine metabolites in man.
作者信息
Belpaire F M, Rosseel M T, Bogaert M G
出版信息
Xenobiotica. 1978 May;8(5):297-300. doi: 10.3109/00498257809060953.
PMID:664752
Abstract
- A gas chromatographic method is described for the quantitative determination of the metabolites of papaverine in urine. 2. The urinary excretion of papaverine metabolites was studied in man. About 50% of the metabolites of papaverine are excreted in the urine within 48 h. 6-Desmethylpapaverine is the major metabolite in the urine. The metabolites are excreted almost completely in conjugated form.
摘要
- 描述了一种用于定量测定尿液中罂粟碱代谢物的气相色谱法。2. 对人体中罂粟碱代谢物的尿排泄情况进行了研究。罂粟碱的代谢物约50%在48小时内随尿液排出。6-去甲基罂粟碱是尿液中的主要代谢物。这些代谢物几乎完全以结合形式排出。
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