德国黑森州人群中的备解素因子B多态性
Properdin factor b-polymorphism in the population of Hessen, Germany.
作者信息
Kühnl P, Spielmann W
出版信息
Z Rechtsmed. 1978 May 29;81(2):125-31. doi: 10.1007/BF00203872.
The polymorphism of properdin factor B (Bf, C3 proactivator) in a population sample from Hessen, Germany has been investigated by agarose gel electrophoresis and immunofixation. In 522 unrelated individuals seven different phenotypes were observed and the following allele frequencies calculated: BfS = 0.7998, BfF = 0.1772, BfS0.7 = 0.0163 and BfF1 = 0.0077. Investigations of 100 families with 198 children and 30 mother-child combinations support the assumed autosomal codominant way of inheritance.
采用琼脂糖凝胶电泳和免疫固定法，对来自德国黑森州人群样本中的备解素因子B（Bf，C3前活化剂）多态性进行了研究。在522名无亲缘关系的个体中，观察到7种不同的表型，并计算出以下等位基因频率：BfS = 0.7998，BfF = 0.1772，BfS0.7 = 0.0163，BfF1 = 0.0077。对100个家庭（198名儿童和30对母婴组合）的调查支持了假定的常染色体共显性遗传方式。
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