等电聚焦法在Bf系统研究中的应用：BfF等位基因两种常见亚型的存在
Isoelectrofocusing in the study of the Bf system: existence of two common subtypes of the BfF allele.
作者信息
Geserick G, Patzelt D, Schröder H, Nagai T
出版信息
Vox Sang. 1983 Mar;44(3):178-82. doi: 10.1111/j.1423-0410.1983.tb01882.x.
Abstract
The inherited polymorphism of the properdin factor B (Bf system) was studied by isoelectrofocusing in polyacrylamide gel (PAGIF, pH range 5.0-8.0), followed by immunofixation. Using the described technique, two different subtypes of F bands are visible (designated as F' and F"). Studies of 13 families and 48 mother-child pairs are not in contradiction to the assumption of a codominant inheritance by two alleles (BfF' and BfF") at a single locus.
摘要
通过在聚丙烯酰胺凝胶中进行等电聚焦（pH范围5.0 - 8.0的聚丙烯酰胺凝胶等电聚焦，PAGIF），随后进行免疫固定，研究了备解素因子B（Bf系统）的遗传多态性。使用所述技术，可以看到F带的两种不同亚型（指定为F'和F"）。对13个家庭和48对母婴的研究与单个基因座上两个等位基因（BfF'和BfF"）共显性遗传的假设并不矛盾。
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