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一种在大鼠中制造慢性胃瘘并收集胃液的新方法。

A new method of producing chronic gastric fistula and collection of gastric juice in rats.

作者信息

Małecki I

出版信息

Acta Physiol Pol. 1978 Jan-Feb;29(1):79-86.

PMID:665252
Abstract

A method of producing chronic gastric fistula and collection of gastric juice in rats. Acta Physiol. Pol., 1978, 29 (1): 79-86. A kind of material suitable for making different parts of the gastric fistula as well as their shape and size have been established. Organic glass (plexiglas) was used for making the cannula. A twisted-on cap of stainless steel protected the mouth of the fistula. This cap secured also the possibility of directly attaching a vessel for collection of gastric juice to the orifice of the cannula. The vessel was made of plexiglas and owing to its shape and dimensions it did not impede the rat's movements during the investigations. A disc of nylon net glued on to the external wall of the cannula prevented leaking of the fistula and its consequences. The fistula produced in this way showed a considerable durability and the vessel made it possible to investigate gastric secretion in a freely moving animal under physiological conditions or under any chosen experimental conditions.

摘要

一种在大鼠身上制造慢性胃瘘并收集胃液的方法。《波兰生理学报》,1978年,29(1):79 - 86。已确定了一种适用于制作胃瘘不同部位及其形状和尺寸的材料。有机玻璃(丙烯酸树脂玻璃)用于制作插管。一个拧上的不锈钢帽保护瘘口。这个帽还确保了将用于收集胃液的容器直接连接到插管口的可能性。该容器由有机玻璃制成,由于其形状和尺寸,在研究过程中不妨碍大鼠活动。一块粘在插管外壁上的尼龙网圆盘可防止瘘管渗漏及其后果。以这种方式制造的瘘管具有相当的耐用性,并且该容器使得在生理条件下或任何选定的实验条件下对自由活动的动物的胃分泌进行研究成为可能。

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