Leino M, Antikainen R, Airaksinen M M, Tuovinen E, Kari I
Acta Ophthalmol (Copenh). 1983 Dec;61(6):1029-36. doi: 10.1111/j.1755-3768.1983.tb01491.x.
6-Methoxy-1,2,3,4-tetrahydro-beta-carboline (6-MeO-THBC) is a condensation product of 5-methoxytryptamine and formaldehyde. It possesses diverse biochemical and pharmacological properties and has been suggested to act as a neuromodulator. 6-MeO-THBC has been shown to occur in various tissues including the retina in animals and human beings. The present results show that the mouse and rat retina as well as other tissues take up 14C-labelled 6-MeO-THBC injected intravenously or intravitreally. The retinal concentrations show a prompt rise after the injection and significant levels are maintained after 2 days.
6-甲氧基-1,2,3,4-四氢-β-咔啉（6-MeO-THBC）是5-甲氧基色胺与甲醛的缩合产物。它具有多种生化和药理特性，有人认为它可作为一种神经调节剂。研究表明，6-MeO-THBC存在于包括动物和人类视网膜在内的各种组织中。目前的研究结果显示，小鼠和大鼠的视网膜以及其他组织会摄取静脉注射或玻璃体内注射的14C标记的6-MeO-THBC。注射后视网膜浓度迅速升高，2天后仍维持在显著水平。
