[伴刀豆球蛋白A诱导的小鼠淋巴细胞中酸性磷酸酶和N-乙酰-β-葡萄糖苷酶活性的变化]
[Change in acid phosphatase and N-acetyl-beta-glucosaminidase activity in mouse lymphocytes induced by concanavalin A].
作者信息
Drozhennikov V A, Surgaĭ V V, Liashenko V A, Beliakova E A
出版信息
Biull Eksp Biol Med. 1983 Dec;96(12):46-8.
PMID:6661547
Abstract
The treatment with concanavalin A (5 micrograms/ml) of mouse lymphocytes containing 70-72% of T cells entails an increase in the activity of acid phosphatase and a decrease in the activity of N-acetyl-beta-glucosaminidase. These changes were detectable 15 h after lymphocyte incubation with Con A. After 24 h of incubation acid phosphatase activity rose 2-fold whereas that of N-acetyl-beta-glucosaminidase dropped 45-50%. Possible mechanisms of these changes are discussed.
摘要
用伴刀豆球蛋白A（5微克/毫升）处理含70 - 72% T细胞的小鼠淋巴细胞，会使酸性磷酸酶活性增加，N - 乙酰 - β - 氨基葡萄糖苷酶活性降低。淋巴细胞与伴刀豆球蛋白A孵育15小时后可检测到这些变化。孵育24小时后，酸性磷酸酶活性上升2倍，而N - 乙酰 - β - 氨基葡萄糖苷酶活性下降45 - 50%。文中讨论了这些变化可能的机制。
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