• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
In vitro activity of rifampin alone and in combination with nafcillin and Vancomycin against pathogenic strains of Staphylococcus aureus.利福平单独及与萘夫西林和万古霉素联合对金黄色葡萄球菌致病菌株的体外活性。
Antimicrob Agents Chemother. 1978 May;13(5):759-61. doi: 10.1128/AAC.13.5.759.
2
Synergy between vancomycin and nafcillin against Staphylococcus aureus in an in vitro pharmacokinetic/pharmacodynamic model.万古霉素与萘夫西林对金黄色葡萄球菌的体外药代动力学/药效学模型协同作用。
PLoS One. 2012;7(7):e42103. doi: 10.1371/journal.pone.0042103. Epub 2012 Jul 24.
3
In vitro evaluation of clindamycin in combination with oxacillin, rifampin, or vancomycin against Staphylococcus aureus.克林霉素与苯唑西林、利福平或万古霉素联合对金黄色葡萄球菌的体外评价。
Diagn Microbiol Infect Dis. 1986 Feb;4(2):133-8. doi: 10.1016/0732-8893(86)90147-1.
4
Antagonism between nafcillin or oxacillin and rifampin against Staphylococcus aureus.萘夫西林或苯唑西林与利福平对金黄色葡萄球菌的拮抗作用。
Antimicrob Agents Chemother. 1982 Nov;22(5):920-2. doi: 10.1128/AAC.22.5.920.
5
An evaluation of the bactericidal activity of ampicillin/sulbactam, piperacillin/tazobactam, imipenem or nafcillin alone and in combination with vancomycin against methicillin-resistant Staphylococcus aureus (MRSA) in time-kill curves with infected fibrin clots.在感染性纤维蛋白凝块的时间-杀菌曲线中，评估氨苄西林/舒巴坦、哌拉西林/他唑巴坦、亚胺培南或萘夫西林单独以及与万古霉素联合对耐甲氧西林金黄色葡萄球菌（MRSA）的杀菌活性。
J Antimicrob Chemother. 1997 Apr;39(4):515-8. doi: 10.1093/jac/39.4.515.
6
Serum bactericidal activity of rifampin in combination with other antimicrobial agents against Staphylococcus aureus.利福平与其他抗菌药物联合对金黄色葡萄球菌的血清杀菌活性。
Antimicrob Agents Chemother. 1986 Apr;29(4):611-3. doi: 10.1128/AAC.29.4.611.
7
Disparity between timed-kill and checkerboard methods for determination of in vitro bactericidal interactions of vancomycin plus rifampin versus methicillin-susceptible and -resistant Staphylococcus aureus.在测定万古霉素联合利福平对甲氧西林敏感和耐药金黄色葡萄球菌的体外杀菌相互作用时，时间杀菌法与棋盘法之间的差异
Antimicrob Agents Chemother. 1984 Aug;26(2):220-3. doi: 10.1128/AAC.26.2.220.
8
Differences in ability of cell-wall antibiotics to suppress emergence of rifampicin resistance in Staphylococcus aureus.
J Antimicrob Chemother. 1985 Feb;15(2):201-7. doi: 10.1093/jac/15.2.201.
9
Impact of high-inoculum Staphylococcus aureus on the activities of nafcillin, vancomycin, linezolid, and daptomycin, alone and in combination with gentamicin, in an in vitro pharmacodynamic model.在体外药效学模型中，高接种量金黄色葡萄球菌对萘夫西林、万古霉素、利奈唑胺和达托霉素单独及与庆大霉素联合使用时活性的影响。
Antimicrob Agents Chemother. 2004 Dec;48(12):4665-72. doi: 10.1128/AAC.48.12.4665-4672.2004.
10
In vitro activity of cefmenoxime, cefotaxime, latamoxef, cefazolin, nafcillin and vancomycin against 53 endocarditis and bacteremic strains of Staphylococcus aureus.
Chemotherapy. 1984;30(5):328-30. doi: 10.1159/000238288.

引用本文的文献

1
Successful Treatment of Infective Endocarditis With Oral Antibiotics: A Case Report.口服抗生素成功治疗感染性心内膜炎：一例报告
Cureus. 2023 Aug 15;15(8):e43514. doi: 10.7759/cureus.43514. eCollection 2023 Aug.
2
Methicillin-Resistant Staphylococcus aureus Prosthetic Valve Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management.耐甲氧西林金黄色葡萄球菌人工心脏瓣膜心内膜炎：病理生理学、流行病学、临床表现、诊断和治疗。
Clin Microbiol Rev. 2019 Feb 13;32(2). doi: 10.1128/CMR.00041-18. Print 2019 Mar 20.
3
msaABCR operon is involved in persister cell formation in Staphylococcus aureus.msaABCR 操纵子参与金黄色葡萄球菌持久细胞的形成。
BMC Microbiol. 2017 Nov 22;17(1):218. doi: 10.1186/s12866-017-1129-9.
4
Combination of alpha-melanocyte stimulating hormone with conventional antibiotics against methicillin resistant Staphylococcus aureus.α-黑素细胞刺激素联合常规抗生素治疗耐甲氧西林金黄色葡萄球菌。
PLoS One. 2013 Sep 9;8(9):e73815. doi: 10.1371/journal.pone.0073815. eCollection 2013.
5
Influence of rifampin therapy on serum bactericidal activity in the presence of cloxacillin and vancomycin.利福平治疗对在氯唑西林和万古霉素存在情况下血清杀菌活性的影响。
Can J Infect Dis. 1990 Summer;1(2):41-7. doi: 10.1155/1990/357189.
6
Use of rifampin in persistent coagulase negative staphylococcal bacteremia in neonates.利福平在新生儿持续凝固酶阴性葡萄球菌菌血症中的应用。
BMC Pediatr. 2010 Nov 19;10:84. doi: 10.1186/1471-2431-10-84.
7
Rifampin combination therapy for nonmycobacterial infections.利福平联合疗法治疗非分枝杆菌感染。
Clin Microbiol Rev. 2010 Jan;23(1):14-34. doi: 10.1128/CMR.00034-09.
8
The management of infection and colonization due to methicillin-resistant Staphylococcus aureus: A CIDS/CAMM position paper.耐甲氧西林金黄色葡萄球菌感染与定植的管理：一份加拿大感染病学会/加拿大抗菌药物管理协会立场文件
Can J Infect Dis. 2004 Jan;15(1):39-48. doi: 10.1155/2004/531434.
9
Efficacy of high doses of levofloxacin in experimental foreign-body infection by methicillin-susceptible Staphylococcus aureus.高剂量左氧氟沙星对甲氧西林敏感金黄色葡萄球菌所致实验性异物感染的疗效
Antimicrob Agents Chemother. 2006 Dec;50(12):4011-7. doi: 10.1128/AAC.00523-06. Epub 2006 Oct 2.
10
Pharmacodynamics of vancomycin and other antimicrobials in patients with Staphylococcus aureus lower respiratory tract infections.万古霉素及其他抗菌药物在金黄色葡萄球菌下呼吸道感染患者中的药效学
Clin Pharmacokinet. 2004;43(13):925-42. doi: 10.2165/00003088-200443130-00005.

本文引用的文献

1
Bacteriologic studies of rifampin, a new semisynthetic antibiotic.新型半合成抗生素利福平的细菌学研究
J Infect Dis. 1969 Feb;119(2):132-7. doi: 10.1093/infdis/119.2.132.
2
Combined rifampicin and erythromycin for bacterial endocarditis.利福平与红霉素联合治疗细菌性心内膜炎。
Br Med J. 1970 Nov 14;4(5732):410-1. doi: 10.1136/bmj.4.5732.410.
3
Serial dilution antibiotic sensitivity testing with the microtitrator system.使用微量滴定仪系统进行系列稀释抗生素敏感性测试。
Am J Clin Pathol. 1966 May;45(5):548-51. doi: 10.1093/ajcp/45.5.548.
4
Killing of intraleukocytic Staphylococcus aureus by rifampin: in-vitro and in-vivo studies.利福平对白细胞内金黄色葡萄球菌的杀灭作用：体外和体内研究
J Infect Dis. 1972 May;125(5):486-90. doi: 10.1093/infdis/125.5.486.
5
Therapy of experimental staphylococcal infection with antibiotic combinations.用抗生素组合治疗实验性葡萄球菌感染。
J Lab Clin Med. 1974 Feb;83(2):241-8.
6
Antibiotic synergy in experimental infection with Pseudomonas. II. The effect of carbenicillin, cephalothin, or cephanone combined with tobramycin or gentamicin.铜绿假单胞菌实验性感染中的抗生素协同作用。II. 羧苄西林、头孢噻吩或头孢乙腈与妥布霉素或庆大霉素联合使用的效果。
J Infect Dis. 1974 Feb;129(2):124-33. doi: 10.1093/infdis/129.2.124.
7
Treatment of experimental staphylococcal infection with rifampin.利福平治疗实验性葡萄球菌感染
Antimicrob Agents Chemother. 1972 Sep;2(3):195-200. doi: 10.1128/AAC.2.3.195.
8
Enhancement of the effects of anti-staphylococcal antibiotics by aminoglycosides.氨基糖苷类药物增强抗葡萄球菌抗生素的效果。
Antimicrob Agents Chemother. 1974 Dec;6(6):802-6. doi: 10.1128/AAC.6.6.802.
9
Synergistic effects of oleandomycin and rifamycin SV in experimental staphylococcal septicaemia in rabbits.竹桃霉素和利福霉素SV对兔实验性葡萄球菌败血症的协同作用
Infection. 1974;2(3):160-1. doi: 10.1007/BF01642237.
10
Combination antibiotic therapy in staphylococcal endocarditis. The use of methicillin sodium-gentamicin sulfate therapy.
Arch Intern Med. 1976 Apr;136(4):480-3.

利福平单独及与萘夫西林和万古霉素联合对金黄色葡萄球菌致病菌株的体外活性。

In vitro activity of rifampin alone and in combination with nafcillin and Vancomycin against pathogenic strains of Staphylococcus aureus.

作者信息

Tuazon C U, Lin M Y, Sheagren J N

出版信息

Antimicrob Agents Chemother. 1978 May;13(5):759-61. doi: 10.1128/AAC.13.5.759.

DOI:10.1128/AAC.13.5.759
PMID:666300
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC352328/
Abstract

Twenty strains of Staphylococcus aureus isolated from patients with endocarditis were examined in vitro for susceptibility to rifampin, nafcillin, and vancomycin and to combinations of rifampin with nafcillin or vancomycin. Minimum bactericidal concentrations of rifampin ranged from 0.0031 to 0.0125 mug/ml, of nafcillin ranged from 0.078 to 0.312 mug/ml, and of vancomycin ranged from 0.312 to 1.25 mug/ml. The combination of rifampin with nafcillin was synergistic for 12 strains; the combination of rifampin plus vancomycin was synergistic for 5 of the isolates.

摘要

对从心内膜炎患者中分离出的20株金黄色葡萄球菌进行了体外试验，检测其对利福平、萘夫西林和万古霉素以及利福平与萘夫西林或万古霉素联合用药的敏感性。利福平的最低杀菌浓度范围为0.0031至0.0125微克/毫升，萘夫西林的最低杀菌浓度范围为0.078至0.312微克/毫升，万古霉素的最低杀菌浓度范围为0.312至1.25微克/毫升。利福平与萘夫西林联合用药对12株菌株具有协同作用；利福平加万古霉素联合用药对5株分离株具有协同作用。