Damian E, Ianăş O, Bădescu I
Endocrinologie. 1983 Oct-Dec;21(4):257-9.
The effect of a pineal treatment on rat testosterone under conditions of exogenous HCG stimulation was followed-up. Administration of 2 ml/day/animal of a melatonin-free pineal extract for 3 days lowered by 23% (p less than 0.01) the serum level and by 32% (p less than 0.02) the testis content in testosterone, both values being increased by concomitant administration of 50 UI HCG per animal. In other words, the melatonin-free pineal extract inhibited partially the testis response to HCG. The antiandrogenic action of the pineal extract is discussed.
对外源性人绒毛膜促性腺激素（HCG）刺激条件下松果体治疗对大鼠睾酮的影响进行了随访。以2毫升/天/动物的剂量给予褪黑素-free松果体提取物，持续3天，可使血清睾酮水平降低23%（p<0.01），睾丸睾酮含量降低32%（p<0.02），而每只动物同时给予50国际单位HCG可使上述两个值升高。换句话说，褪黑素-free松果体提取物部分抑制了睾丸对HCG的反应。文中讨论了松果体提取物的抗雄激素作用。
