Cheung A S, Gray B F
J Muscle Res Cell Motil. 1983 Dec;4(6):615-23. doi: 10.1007/BF00712156.
The set of kinetic equations that defines a deterministic model of muscle contraction, based on the sliding filament hypothesis in which the relative sliding velocity is an independent variable, is numerically integrated under the simulated conditions of sinusoidal length perturbation. The frequency response curve of phase angle and dynamic stiffness are in agreement with experimental curves. The resultant mean tension per cycle is lower than the unperturbed steady-state tension. The magnitude of the negative tension deviation is greater when either the amplitude or the frequency of the oscillation is increased. The tension-time curve differs from a simple sine when the perturbing frequency is in the vicinity of the stiffness minimum. These consequences are in agreement with the few experimental results that are available.
基于肌丝滑行假说(其中相对滑行速度是一个自变量)定义肌肉收缩确定性模型的动力学方程组,在正弦长度微扰的模拟条件下进行数值积分。相角和动态刚度的频率响应曲线与实验曲线一致。每个周期的合成平均张力低于未受干扰的稳态张力。当振荡的幅度或频率增加时,负张力偏差的幅度更大。当微扰频率在刚度最小值附近时,张力-时间曲线不同于简单的正弦曲线。这些结果与现有的少数实验结果一致。