Perdrix A, Pellet F, Vincent M, De Gaudemaris R, Mallion J M
Toxicol Eur Res. 1983 Sep;5(5):233-40.
Cobalt urinary excretion should be a good way to know the level of exposition of subjects submitted to hard metals. The study is done on 28 workers of 3 different workrooms. Sunday 24 hours diuresis is retained. For 5 workers, the urinary cobalt measurements are done from samples made at the beginning and the end of work during 5 days. Atmospheric dust measurements are realized in different points of the 3 workrooms (individual and general samples). For measures atomic absorption spectrometry is used. The results show a good correlation between cobalt exposure and urinary concentrations. Friday evening urinary cobalt is a good expression of week exposure. The results obtained well correlate with those of others authors. Cobalt urinary measures are proposed for supervision of workers exposed to hard metals.
尿钴排泄应该是了解接触硬质金属的受试者暴露水平的一种好方法。该研究针对3个不同工作室的28名工人进行。收集周日24小时的尿液。对5名工人，在5天的工作开始和结束时采集样本进行尿钴测量。在3个工作室的不同地点进行大气粉尘测量（个人和总体样本）。测量采用原子吸收光谱法。结果表明钴暴露与尿中浓度之间有良好的相关性。周五晚上的尿钴是一周暴露情况的良好指标。所得结果与其他作者的结果相关性良好。建议通过尿钴测量来监测接触硬质金属的工人。
