• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

风湿性疾病中维生素E与脂质过氧化物状态的研究。

Investigations on vitamin E and lipid peroxide status in rheumatic diseases.

作者信息

Mezes M, Bartosiewicz G

出版信息

Clin Rheumatol. 1983 Sep;2(3):259-63. doi: 10.1007/BF02041400.

DOI:10.1007/BF02041400
PMID:6678699
Abstract

Patients of both sexes suffering from two types of rheumatic diseases-- rheumatoid arthritis and osteoarthrosis--were examined. Healthy volunteers of similar age served as controls. No significant difference was found in the plasma vitamin E content of the patients. Plasma malondialdehyde content was significantly higher /P less than 0.001/ in both sexes in the RA and OA groups as compared to the controls. Plasma catalase activity in both sexes was significantly higher (P less than 0.01) in RA and OA groups while RBC glutathione-peroxidase showed significantly (P less than 0.001) higher activity only in the female RA group, as compared to the control subjects. A difference was found between RA and OA groups in malondialdehyde content and in glutathione-peroxidase activity in subjects of both sexes.

摘要

对患有两种风湿性疾病——类风湿性关节炎和骨关节炎的男女患者进行了检查。年龄相仿的健康志愿者作为对照。未发现患者血浆维生素E含量有显著差异。与对照组相比,类风湿性关节炎(RA)组和骨关节炎(OA)组的男女血浆丙二醛含量均显著更高(P<0.001)。与对照组相比,RA组和OA组男女的血浆过氧化氢酶活性均显著更高(P<0.01),而仅女性RA组的红细胞谷胱甘肽过氧化物酶活性显著更高(P<0.001)。在男女受试者的丙二醛含量和谷胱甘肽过氧化物酶活性方面,RA组和OA组之间存在差异。

相似文献

1
Investigations on vitamin E and lipid peroxide status in rheumatic diseases.风湿性疾病中维生素E与脂质过氧化物状态的研究。
Clin Rheumatol. 1983 Sep;2(3):259-63. doi: 10.1007/BF02041400.
2
Changes in lipid, peroxide, and anti-oxidant blood levels during piroxicam (Hotemin) treatment.
Ther Hung. 1993;41(2):67-71.
3
Vitamin E content and lipid peroxidation of blood in some chronic inflammatory diseases.某些慢性炎症性疾病患者血液中的维生素E含量与脂质过氧化反应
Acta Physiol Hung. 1987;69(1):133-8.
4
Plasma total antioxidant capacity, lipid peroxidation, and erythrocyte antioxidant enzyme activities in patients with rheumatoid arthritis and osteoarthritis.类风湿性关节炎和骨关节炎患者的血浆总抗氧化能力、脂质过氧化及红细胞抗氧化酶活性
Clin Biochem. 2005 Nov;38(11):981-6. doi: 10.1016/j.clinbiochem.2005.08.003. Epub 2005 Sep 16.
5
Levels of plasma lipid peroxide products and antioxidant status in rheumatoid arthritis.类风湿关节炎患者血浆脂质过氧化物产物水平及抗氧化状态
Southeast Asian J Trop Med Public Health. 2000 Jun;31(2):335-8.
6
Effect of thyrotropin (TSH) treatment on the vitamins A and E and lipid-peroxide status of domestic fowl.促甲状腺素(TSH)治疗对家禽维生素A、维生素E及脂质过氧化物状态的影响
Acta Vet Hung. 1984;32(3-4):175-80.
7
Plasma lipid peroxidation and antioxidant levels in patients with rheumatoid arthritis.类风湿关节炎患者的血浆脂质过氧化和抗氧化水平
Cell Biochem Funct. 2004 Jan-Feb;22(1):53-7. doi: 10.1002/cbf.1055.
8
[Lipid peroxides and antioxidants in the blood of patients with arteriosclerotic circulatory disorders].[动脉硬化性循环障碍患者血液中的脂质过氧化物与抗氧化剂]
Z Gesamte Inn Med. 1985 May 1;40(9):276-8.
9
Serum vitamin E, lipid peroxide and glutathione peroxidase in patients with chronic pancreatitis.
Clin Chim Acta. 1981 Feb 19;110(1):121-5. doi: 10.1016/0009-8981(81)90308-9.
10
Erythrocyte antioxidant enzymes are reduced in patients with rheumatoid arthritis.类风湿关节炎患者的红细胞抗氧化酶减少。
J Rheumatol. 1988 Nov;15(11):1628-31.

引用本文的文献

1
Lipid peroxidation and antioxidant status in patients with rheumatoid arthritis.类风湿关节炎患者的脂质过氧化与抗氧化状态
Indian J Clin Biochem. 2008 Jan;23(1):41-4. doi: 10.1007/s12291-008-0010-x. Epub 2008 Mar 6.
2
Correlation of fatty acid composition of adipose tissue lipids and serum phosphatidylcholine and serum concentrations of micronutrients with disease duration in rheumatoid arthritis.类风湿关节炎患者脂肪组织脂质和血清磷脂酰胆碱的脂肪酸组成以及血清微量营养素浓度与疾病持续时间的相关性
Ann Rheum Dis. 1990 Nov;49(11):901-5. doi: 10.1136/ard.49.11.901.

本文引用的文献

1
A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase.一种用于测量过氧化氢被过氧化氢酶分解的分光光度法。
J Biol Chem. 1952 Mar;195(1):133-40.
2
SERUM VITAMIN E LEVELS IN A NORMAL ADULT POPULATION IN THE WASHINGTON, D. C., AREA.华盛顿特区正常成年人群的血清维生素E水平。
Proc Soc Exp Biol Med. 1964 Oct;117:131-3. doi: 10.3181/00379727-117-29515.
3
1958 Revision of diagnostic criteria for rheumatoid arthritis.1958年类风湿关节炎诊断标准修订版。
Bull Rheum Dis. 1958 Dec;9(4):175-6.
4
Antioxidants as agents reducing the toxicity of indomethacin.抗氧化剂作为降低吲哚美辛毒性的药物。
Acta Biol Med Ger. 1980;39(6):717-21.
5
Investigations concerning vitamin A transport in rheumatic diseases.
Clin Rheumatol. 1982 Sep;1(3):190-3. doi: 10.1007/BF02042773.
6
Phagocyte-generated oxygen metabolites and cellular injury.吞噬细胞产生的氧代谢产物与细胞损伤。
Lab Invest. 1982 Jul;47(1):5-18.
7
Effects of vitamin E on mixed lymphocyte cultures.维生素E对混合淋巴细胞培养的影响。
Ann Nutr Metab. 1982;26(3):171-7. doi: 10.1159/000176560.
8
Estimation of product of lipid peroxidation (malonyl dialdehyde) in biochemical systems.生物化学系统中脂质过氧化产物(丙二醛)的测定。
Anal Biochem. 1966 Aug;16(2):359-64. doi: 10.1016/0003-2697(66)90167-9.
9
Arthritis induced in rabbits by lysates of granulocyte lysosomes.由粒细胞溶酶体裂解物诱导家兔产生的关节炎。
Arthritis Rheum. 1969 Apr;12(2):103-16. doi: 10.1002/art.1780120207.
10
Free radicals and inflammation: protection of synovial fluid by superoxide dismutase.自由基与炎症:超氧化物歧化酶对滑液的保护作用
Science. 1974 Aug 9;185(4150):529-31. doi: 10.1126/science.185.4150.529.