Mygind N, Dirksen A, Johnsen N J, Weeke B
Clin Otolaryngol Allied Sci. 1978 May;3(2):189-96. doi: 10.1111/j.1365-2273.1978.tb00681.x.
Allergen skin testing, eosinophil counting in blood and nasal smear and serum IgE determination were performed in patients with simple perennial rhinitis, and in patients with rhinitis and asthma. The results were compared with those obtained in normal controls. As a positive skin test was demonstrated in 40% of patients with simple rhinitis and in 88% of patients with rhinitis and asthma, skin testing is considered relevant in all patients with perennial rhinitis. While blood eosinophil count and serum IgE level were elevated in a fair proportion of asthmatic patients, only a few subjects with simple perennial rhinitis had an elevated level, and the diagnostic values of these tests is questionable. On the other hand, examination of a nasal smear for eosinophils could usually separate the patients from the controls. The study emphasizes the importance of making a distinction between simple perennial rhinitis and perennial rhinitis associated with other symptoms and diseases.
对单纯性常年性鼻炎患者、鼻炎合并哮喘患者进行了变应原皮肤试验、血液嗜酸性粒细胞计数、鼻涂片检查及血清IgE测定，并将结果与正常对照组进行比较。由于40%的单纯性鼻炎患者和88%的鼻炎合并哮喘患者皮肤试验呈阳性，因此皮肤试验被认为对所有常年性鼻炎患者都有意义。虽然相当一部分哮喘患者的血液嗜酸性粒细胞计数和血清IgE水平升高，但只有少数单纯性常年性鼻炎患者的水平升高，这些检查的诊断价值值得怀疑。另一方面，鼻涂片嗜酸性粒细胞检查通常可以将患者与对照组区分开来。该研究强调了区分单纯性常年性鼻炎与伴有其他症状和疾病的常年性鼻炎的重要性。
