十二指肠内途径给予胞磷胆碱对大鼠心肺系统的作用。
Action of CDP-choline by intraduodenal route on rat cardiorespiratory system.
作者信息
Brasó M A, Sacristán A, Ortiz J A
出版信息
Arzneimittelforschung. 1983;33(7A):1043-5.
The influence of an acute treatment with cytidine diphosphate choline (CDP-choline, citicoline, Somazina) by intraduodenal route on cardiovascular and respiratory parameters in anesthetized rats is studied. No differences as compared with controls were observed in heart and respiratory rates. The values in arterial pressure and respiratory flow for CDP-choline groups were observed to be near the basal values. The inspiratory flow shows a statistically significant difference (approaching basal values) as compared with the decrease in controls.
研究了通过十二指肠途径急性给予胞二磷胆碱（CDP - 胆碱、胞磷胆碱、索马西纳）对麻醉大鼠心血管和呼吸参数的影响。与对照组相比，心率和呼吸频率未观察到差异。观察到CDP - 胆碱组的动脉压和呼吸流量值接近基础值。与对照组的降低相比，吸气流量显示出统计学上的显著差异（接近基础值）。
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