Lewine R, Burbach D, Meltzer H Y
Am J Psychiatry. 1984 Jan;141(1):84-7. doi: 10.1176/ajp.141.1.84.
Contrary to earlier epidemiological data, recent evidence points to a significantly greater proportion of men than women among schizophrenic patients diagnosed by current restrictive criteria. In this study, the authors analyzed the effect of using six different diagnostic systems (varying in their stringency) on the male to female ratio of schizophrenia among 387 inpatients. Diagnostic criteria representing a broad conceptualization of schizophrenia, such as the New Haven Schizophrenia Index, consistently yielded equal rates of schizophrenia among men and women. Those diagnostic systems representing more stringently defined schizophrenia, such as the Research Diagnostic Criteria, consistently yielded a male to female ratio significantly greater than the male to female ratio of the total sample.
与早期的流行病学数据相反，最近的证据表明，按照当前严格标准诊断出的精神分裂症患者中，男性比例显著高于女性。在本研究中，作者分析了使用六种不同诊断系统（严格程度各异）对387名住院患者中精神分裂症的男女比例的影响。代表精神分裂症宽泛概念化的诊断标准，如新 Haven 精神分裂症指数，始终得出男女精神分裂症发病率相等的结果。而那些代表更严格定义的精神分裂症的诊断系统，如研究诊断标准，始终得出的男女比例显著高于总样本中的男女比例。
