Luft B J, Remington J S
Arch Intern Med. 1984 Jan;144(1):53-6. doi: 10.1001/archinte.1984.00350130059012.
Studies were performed to determine how frequently acute infections with Toxoplasma gondii occur among family members of patients with acute acquired lymphadenopathic toxoplasmosis. In five of the nine families studied, more than one family member had serologic evidence of recent acute infection with T gondii. In three of the families, the immunoglobulin M and immunoglobulin G antibody titers to T gondii among infected family members were similar irrespective of whether lymphadenopathy was present. Lymphadenopathy developed in one family member in each of two families (families VIII and IX) three and eight months after lymphadenopathy had developed in the index case (proband). These results suggest that common-source outbreaks occur with surprising frequency among family members of patients with lymphadenopathic toxoplasmosis and that the humoral response is similar with different manifestations of the infection.
开展了多项研究，以确定急性获得性淋巴结病型弓形虫病患者的家庭成员中急性弓形虫感染的发生频率。在所研究的9个家庭中，有5个家庭不止一名家庭成员有近期急性弓形虫感染的血清学证据。在其中3个家庭中，无论是否存在淋巴结病，受感染家庭成员中针对弓形虫的免疫球蛋白M和免疫球蛋白G抗体滴度相似。在两个家庭（家庭VIII和IX）中，各有一名家庭成员在索引病例（先证者）出现淋巴结病3个月和8个月后出现了淋巴结病。这些结果表明，在淋巴结病型弓形虫病患者的家庭成员中，共同来源的疫情发生频率惊人，并且感染的不同表现形式的体液反应相似。
