• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Methotrexate enterotoxicity: influence of drug dose and timing in the rat.甲氨蝶呤肠毒性：药物剂量和给药时间对大鼠的影响。
Br J Cancer. 1984 Jan;49(1):97-101. doi: 10.1038/bjc.1984.15.
2
Topical methotrexate alters solute and water transport in the rat jejunum in vivo and rabbit ileum in vitro.局部应用甲氨蝶呤可改变大鼠空肠的体内溶质和水转运以及兔回肠的体外溶质和水转运。
Gut. 1985 Jul;26(7):704-9. doi: 10.1136/gut.26.7.704.
3
Is folate absorption impaired by high dose methotrexate?高剂量甲氨蝶呤会损害叶酸吸收吗？
Br J Cancer. 1983 Feb;47(2):303-5. doi: 10.1038/bjc.1983.40.
4
[Pentagastrin and glucagon effect on water, electrolyte and glucose resorption in human jejunum].[五肽胃泌素和胰高血糖素对人空肠水、电解质及葡萄糖吸收的影响]
Verh Dtsch Ges Inn Med. 1973;79:845-7.
5
Intestinal barrier function and secretion in methotrexate-induced rat intestinal mucositis.甲氨蝶呤诱导的大鼠肠道黏膜炎中的肠道屏障功能与分泌
Dig Dis Sci. 2004 Jan;49(1):65-72. doi: 10.1023/b:ddas.0000011604.45531.2c.
6
Intestinal absorption of glucose immediately after vincristin administration in rats.长春新碱给药后大鼠肠道对葡萄糖的即时吸收情况。
Experientia. 1976 Jun 15;32(6):709-11. doi: 10.1007/BF01919846.
7
Stimulation of intestinal sodium and water transport in vivo by angiotensin II and analogs.血管紧张素II及其类似物对体内肠道钠和水转运的刺激作用。
Endocrinology. 1980 Dec;107(6):1946-53. doi: 10.1210/endo-107-6-1946.
8
Stimulation of water and sodium secretion and inhibition of glucose absorption from the rat jejunum during intraarterial infusions of prostglandins.动脉内输注前列腺素期间对大鼠空肠水和钠分泌的刺激以及对葡萄糖吸收的抑制。
Gut. 1975 Oct;16(10):759-65. doi: 10.1136/gut.16.10.759.
9
Effect of secretin and caerulein on the absorption of water, electrolytes and glucose from the jejunum of dogs.促胰液素和雨蛙肽对犬空肠水、电解质及葡萄糖吸收的影响。
Digestion. 1986;35(4):205-10. doi: 10.1159/000199369.
10
Modulated pharmacokinetics and increased small intestinal toxicity of methotrexate in bilirubin-treated rats.胆红素处理大鼠中甲氨蝶呤的药代动力学调制和小肠毒性增加。
J Pharm Pharmacol. 2011 Feb;63(2):206-13. doi: 10.1111/j.2042-7158.2010.01213.x.

引用本文的文献

1
Soy Isoflavones in Integrative Oncology: Increased Efficacy and Decreased Toxicity of Cancer Therapy.大豆异黄酮在肿瘤整合医学中的应用：提高癌症治疗的疗效，降低毒性。
Integr Cancer Ther. 2019 Jan-Dec;18:1534735419835310. doi: 10.1177/1534735419835310.
2
Joining the DoTS: new approach to classifying adverse drug reactions.加入药物不良反应术语集：药物不良反应分类的新方法。
BMJ. 2003 Nov 22;327(7425):1222-5. doi: 10.1136/bmj.327.7425.1222.

本文引用的文献

1
Morphologic alterations induced by methotrexate in the mucosa of human proximal intestine. I. Serial observations by light microscopy.
Gastroenterology. 1962 Mar;42:295-305.
2
Effects of aminopterin administration on the respiration and morphology of the gastrointestinal mucosa of rats.
J Lab Clin Med. 1954 Apr;43(4):583-94.
3
Response of the rat small-intestine epithelium to methotrexate.大鼠小肠上皮对甲氨蝶呤的反应。
Gut. 1980 Jun;21(6):486-92. doi: 10.1136/gut.21.6.486.
4
Enteropathy complicating maintenance therapy in acute lymphoblastic leukaemia.急性淋巴细胞白血病维持治疗中并发的肠病
Arch Dis Child. 1982 Sep;57(9):663-7. doi: 10.1136/adc.57.9.663.
5
Jejunal crypt cell abnormalities associated with methotrexate treatment in children with acute lymphoblastic leukaemia.急性淋巴细胞白血病患儿甲氨蝶呤治疗相关的空肠隐窝细胞异常
J Clin Pathol. 1982 Nov;35(11):1272-7. doi: 10.1136/jcp.35.11.1272.
6
Small bowel enterocyte abnormalities caused by methotrexate treatment in acute lymphoblastic leukaemia of childhood.甲氨蝶呤治疗儿童急性淋巴细胞白血病引起的小肠肠上皮细胞异常。
J Clin Pathol. 1981 Jul;34(7):790-5. doi: 10.1136/jcp.34.7.790.
7
Enterotoxic effect of methotrexate: does it influence the drug's absorption in children with acute lymphoblastic leukaemia?甲氨蝶呤的肠毒性作用：它会影响急性淋巴细胞白血病患儿对该药物的吸收吗？
Br Med J (Clin Res Ed). 1981 Apr 18;282(6272):1276-7. doi: 10.1136/bmj.282.6272.1276.
8
Methotrexate enteropathy.甲氨蝶呤肠病
Lancet. 1981 Jan 17;1(8212):164. doi: 10.1016/s0140-6736(81)90760-1.
9
The effect of oral methotrexate on the rat intestine.
Biochem Pharmacol. 1966 Oct;15(10):1479-89. doi: 10.1016/0006-2952(66)90193-6.
10
The effects of different bile salts on the absorption of fluid, electrolytes, and monosaccharides in the small intestine of the rat in vivo.不同胆汁盐对大鼠体内小肠中液体、电解质和单糖吸收的影响。
Gut. 1972 Aug;13(8):596-603. doi: 10.1136/gut.13.8.596.

Methotrexate enterotoxicity: influence of drug dose and timing in the rat.

作者信息

Pinkerton C R, Milla P J

出版信息

Br J Cancer. 1984 Jan;49(1):97-101. doi: 10.1038/bjc.1984.15.

DOI:10.1038/bjc.1984.15
PMID:6691903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1976680/
Abstract
摘要