Iacobello C, Ghielmi S, Belloli S, Arosio P, Albertini A
Clin Chem. 1984 Feb;30(2):298-301.
We assessed the accuracy and precision of seven commercial kits for serum ferritin. The concentration of ferritin as determined by these assays for a liver ferritin reference standard, a human heart ferritin standard, and normal sera correlated highly, but the absolute values varied widely. Use of an international reference standard for ferritin to prepare the standard curve greatly diminished the variability, but did not eliminate it. Although the seven kits differed in specificity for various human isoferritins, this did not appear substantially to affect accuracy. Six of the seven kits appeared sufficiently precise for clinical use over a wide range of ferritin concentrations.
我们评估了七种市售血清铁蛋白检测试剂盒的准确性和精密度。这些检测方法测定的肝脏铁蛋白参考标准品、人心脏铁蛋白标准品以及正常血清中铁蛋白的浓度具有高度相关性，但绝对值差异很大。使用铁蛋白国际参考标准品制备标准曲线可大大降低变异性，但并未消除。尽管这七种试剂盒对各种人同工铁蛋白的特异性有所不同，但这似乎并未对准确性产生实质性影响。七种试剂盒中有六种在广泛的铁蛋白浓度范围内似乎具有足够的精密度用于临床。
