Doxanas M T, Green W R
Arch Ophthalmol. 1984 Feb;102(2):245-9. doi: 10.1001/archopht.1984.01040030195025.
The clinical and histopathologic features of 40 cases of sebaceous gland carcinoma include tumors that appeared as a localized lesion (15), diffuse chronic blepharoconjunctivitis (12), recurrent chalazion (eight), and caruncular tumors (two). In three older cases, specimens were submitted with insufficient clinical information. Chronic blepharoconjunctivitis were associated with "pagetoid" involvement of the conjunctive and lid margin. Despite the characteristic pathologic features of sebaceous gland carcinoma, correct diagnosis was given for only 22.5% of tumors on initial pathologic examination. The most common misdiagnoses were basal cell carcinoma (11) and squamous cell carcinoma (ten). Early recognition and diagnosis have substantially reduced tumor mortality. Six (24.0%) tumor deaths were encountered in 25 patients treated prior to 1970. No tumor-related mortality occurred in the 15 patients encountered after 1970.
40例皮脂腺癌的临床和组织病理学特征包括：表现为局限性病变的肿瘤（15例）、弥漫性慢性睑结膜炎（12例）、复发性睑板腺囊肿（8例）和泪阜肿瘤（2例）。在3例老年患者中，提交的标本临床信息不足。慢性睑结膜炎与结膜和睑缘的“派杰样”浸润有关。尽管皮脂腺癌具有特征性的病理特征，但在初次病理检查时，只有22.5%的肿瘤得到了正确诊断。最常见的误诊是基底细胞癌（11例）和鳞状细胞癌（10例）。早期识别和诊断已大幅降低了肿瘤死亡率。1970年以前接受治疗的25例患者中有6例（24.0%）死于肿瘤。1970年以后遇到的15例患者中未发生与肿瘤相关的死亡。
