Yinon U, Koslowe K C, Rassin M I
Curr Eye Res. 1984 Mar;3(3):431-9. doi: 10.3109/02713688408997230.
Monocular closure surgically performed during development by suturing the eyelids induced less hyperopia in the closed eye of light reared kittens (+0.95 Diopters) in comparison to the closed eyes of lid sutured dark reared kittens (+2.61 D). The normal control cats were also slightly hypermetropic (+0.69 D). While a certain proportion of myopic eyes was found in the monocularly closed light reared kittens and in the normal control cats, no one eye was myopic either in the operated or nonoperated dark reared kittens. Lid suture was found to considerably increase the hyperopia also in adult cats. The incidence of astigmatism was 47.0% for the closed eye in the lid sutured light reared kittens and 64.7% for their open eyes; for the lid sutured dark reared kittens the proportions were 45.4% and 54.5%, respectively. The incidence of astigmatism was 20.2% for the eyes of the normal control cats. Axial length of the closed eye of light (19.00 mm) and of dark (19.45 mm) reared kittens was smaller in comparison to that of the normal control cats (20.38 mm). The corneal curvature of the closed eyes of light (8.09 mm) and of the dark (8.64 mm) reared kittens was flatter than in the normal controls (7.11 mm). It is concluded that lid closure in kittens has a corneal effect, accentuating the tendency for hypermetropia naturally occurring in the dark. In the light lid closure results in an imbalanced combination of the corneal and the (axial?) visual deprivation effects, causing a considerable variability in the refractive error with a tendency for cancellation of the naturally occurring hyperopia.
在发育过程中通过缝合眼睑进行的单眼闭合手术，与在黑暗环境中饲养且眼睑缝合的小猫的闭合眼（+2.61屈光度）相比，在明亮环境中饲养的小猫的闭合眼（+0.95屈光度）产生的远视程度更低。正常对照猫也有轻微远视（+0.69屈光度）。虽然在单眼闭合且在明亮环境中饲养的小猫以及正常对照猫中发现了一定比例的近视眼睛，但在黑暗环境中饲养的手术或未手术小猫中均未发现单眼近视。还发现眼睑缝合在成年猫中也会显著增加远视。在明亮环境中饲养且眼睑缝合的小猫中，闭合眼的散光发生率为47.0%，睁开眼为64.7%；在黑暗环境中饲养且眼睑缝合的小猫中，相应比例分别为45.4%和54.5%。正常对照猫眼睛的散光发生率为20.2%。与正常对照猫（20.38毫米）相比，明亮环境中饲养（19.00毫米）和黑暗环境中饲养（19.45毫米）的小猫的闭合眼轴长较短。明亮环境中饲养（8.09毫米）和黑暗环境中饲养（8.64毫米）的小猫的闭合眼角膜曲率比正常对照（7.11毫米）更平坦。结论是，小猫的眼睑闭合具有角膜效应，加剧了在黑暗中自然发生的远视倾向。在明亮环境中，眼睑闭合导致角膜和（轴向？）视觉剥夺效应的不平衡组合，导致屈光不正有相当大的变异性，并有抵消自然发生的远视的趋势。
