Bins M, Burgers P I, Selbach S G, van Wettum T B, Lamers C B, van Tongeren J H
Hepatogastroenterology. 1984 Feb;31(1):41-3.
In a middle-aged group of normal subjects achlorhydria after maximal stimulation with pentagastrin was found in 12 out of 366 males (3%) and 2 out of 198 females (1%); 13 of these 14 (93%) had an elevated serum gastrin, of which nine were more than two times normal. In another 11 persons a moderately elevated serum gastrin - less than two times normal - was found in absence of achlorhydria. At least seven of them had hypochlorhydria. Of 540 persons with a normal serum gastrin one had achlorhydria. Determination of the serum gastrin appeared to be fairly reliable as a method of detecting achlorhydria.
在一组中年正常受试者中,366名男性中有12名(3%)、198名女性中有2名(1%)在经五肽胃泌素最大刺激后出现无胃酸分泌;这14人中的13人(93%)血清胃泌素升高,其中9人超过正常水平两倍。另外11人在无胃酸分泌的情况下血清胃泌素轻度升高——低于正常水平两倍——其中至少7人有胃酸过少。在540名血清胃泌素正常的人中,有1人无胃酸分泌。血清胃泌素测定作为检测无胃酸分泌的一种方法似乎相当可靠。