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两种方法制备的解冻新鲜冰冻血浆中不稳定凝血因子

Labile coagulation factors in thawed fresh frozen plasma prepared by two methods.

作者信息

Kakaiya R M, Morse E E, Panek S

出版信息

Vox Sang. 1984;46(1):44-6. doi: 10.1111/j.1423-0410.1984.tb00046.x.

DOI:10.1111/j.1423-0410.1984.tb00046.x
PMID:6702140
Abstract

Two preparations of fresh frozen plasma were studied. The plasma from CPDA-1 whole blood units was either frozen within 6 h (FFP-I) or 18-20 h (FFP-II) of phlebotomy. Average activity for factor VIII for FFP-I (n = 6) and FFP-II (n = 19) was 102% and 55%, respectively (p less than 0.01). Average activity for factor V and VII in both products was approximately 100%. Factor XI activity (n = 13) in FFP-II averaged 84%. We conclude that FFP-I and FFP-II are equivalent in terms of coagulation factor activity except for factor VIII.

摘要

对两种新鲜冰冻血浆制剂进行了研究。来自CPDA - 1全血单位的血浆在采血后6小时内(FFP - I)或18 - 20小时内(FFP - II)进行冷冻。FFP - I(n = 6)和FFP - II(n = 19)的因子VIII平均活性分别为102%和55%(p小于0.01)。两种产品中因子V和VII的平均活性约为100%。FFP - II中的因子XI活性(n = 13)平均为84%。我们得出结论,除因子VIII外,FFP - I和FFP - II在凝血因子活性方面相当。

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