Slevin M L, Ang L M, Johnston A, Turner P
Cancer Chemother Pharmacol. 1984;12(3):151-3. doi: 10.1007/BF00256536.
A range of clinical and industrial gloves have been evaluated to determine their ability to exclude penetration by cytotoxic drugs. Radiolabelled cyclophosphamide, methotrexate, daunomycin, cytosine arabinoside, and vincristine sulphate were studied in an equilibrium dialysis system in which the glove material was used as the dialysis membrane. The thicker gloves were the most effective, but very little drug crossed any of the gloves tested under laboratory conditions. Further studies to evaluate gloves in conditions of clinical use are now needed.
已经对一系列临床和工业用手套进行了评估,以确定它们阻止细胞毒性药物渗透的能力。在一个平衡透析系统中研究了放射性标记的环磷酰胺、甲氨蝶呤、柔红霉素、阿糖胞苷和硫酸长春新碱,其中手套材料用作透析膜。较厚的手套效果最佳,但在实验室条件下,测试的任何手套都只有极少的药物透过。现在需要进一步研究以评估临床使用条件下的手套。