Campara P, D'Andrea F, Micciolo R, Savonitto C, Tansella M, Zimmermann-Tansella C
Int Arch Occup Environ Health. 1984;53(3):233-46. doi: 10.1007/BF00398816.
The effects of lead exposure on psychological test performance and subjective feelings of well-being were investigated in 40 exposed workers whose PbB levels had never exceeded 60 micrograms/100 ml and in 20 controls matched for sex, age and educational level. The exposed workers were divided into two groups of 20, with recent PbB levels in the range 45-60 micrograms/100 ml or below 35 micrograms/100 ml. The group of workers with the higher PbB levels showed significantly poorer performance and reported more physical symptoms than the other two groups. These differences were unrelated to sociodemographic and personality characteristics. A principal component analysis suggested that the poorer performance was mainly due to an impairment of general functioning and only to some extent to a deterioration in specific functions, such as verbal reasoning and abstraction. Higher lead concentrations were correlated with poorer performance and a higher number of physical complaints. These results indicate that in exposed workers the threshold for impaired performance lies below the blood-lead concentration of 60 micrograms/100 ml, which is the current threshold limit value (TLV).
对40名铅暴露工人(其血铅水平从未超过60微克/100毫升)以及20名在性别、年龄和教育水平上与之匹配的对照组人员,研究了铅暴露对心理测试表现和主观幸福感的影响。将铅暴露工人分为两组,每组20人,一组近期血铅水平在45 - 60微克/100毫升之间,另一组低于35微克/100毫升。血铅水平较高的工人组表现明显较差,且报告的身体症状比其他两组更多。这些差异与社会人口统计学和人格特征无关。主成分分析表明,表现较差主要是由于总体功能受损,仅在一定程度上是由于特定功能(如言语推理和抽象能力)的恶化。较高的铅浓度与较差的表现以及更多的身体不适相关。这些结果表明,在铅暴露工人中,表现受损的阈值低于目前的阈限值(TLV)——血铅浓度60微克/100毫升。