Haenninen H, Hernberg S, Mantere P, Vesanto R, Jalkanen M
J Occup Med. 1978 Oct;20(10):683-9.
In a study of the effects of low lead exposure on psychological performance, 49 exposed workers and 24 controls were given a psychological test battery. All the lead workers had been under regular monitoring during their entire exposure time, and only workers whose maximal blood lead concentration had never exceeded 70 microgram/100 ml were included in the study. At the time of the examination, the mean blood lead level of the exposed group was 32 +/- 11 microgram/100 ml. Comparisons were made both between exposed and nonexposed workers and within the exposed group. In the latter case, the maximal, the average and the actual blood lead concentrations were used as measures of uptake. The most important finding was a significant relationship between impaired psychological performance and lead uptake within the exposed group. The performances that were most affected by lead depended on visual intelligence and visual-motor functions. Age and neuroticism did not explain these relationships. The impairment of psychological performance correlated better with the average than with the maximal or actual blood lead concentration. Considering that no single blood lead concentration had ever exceeded 70 microgram/100 ml, these findings indicate that the threshold for impaired performance lies below that level.
在一项关于低铅暴露对心理表现影响的研究中,对49名暴露工人和24名对照组人员进行了一系列心理测试。所有铅作业工人在整个暴露期间都接受了定期监测,只有最大血铅浓度从未超过70微克/100毫升的工人被纳入研究。在检查时,暴露组的平均血铅水平为32±11微克/100毫升。对暴露工人和未暴露工人之间以及暴露组内部进行了比较。在后一种情况下,将最大、平均和实际血铅浓度用作摄入量的指标。最重要的发现是,暴露组中心理表现受损与铅摄入量之间存在显著关系。受铅影响最大的表现取决于视觉智力和视动功能。年龄和神经质并不能解释这些关系。心理表现的受损与平均血铅浓度的相关性比与最大或实际血铅浓度的相关性更好。考虑到没有一个血铅浓度曾超过70微克/100毫升,这些发现表明,表现受损的阈值低于该水平。