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[异位自体脾移植中的移植预处理与移植大小]

[Transplant conditioning and transplant size in heterotopic autologous spleen transplantation].

作者信息

Pimpl W, Wayand W, Thalhammer J, Trost A

出版信息

Langenbecks Arch Chir. 1984;362(1):5-16. doi: 10.1007/BF01263315.

DOI:10.1007/BF01263315
PMID:6708684
Abstract

In an experimental study we compared two methods of preparing transplants in rabbits (n = 66): 4-5 splenic fragments with a thickness of 1 mm and graduated weight (5-800 mg) were attached onto the peritoneal peritoneum. Splenic homogenates with increasing weight (5-800 mg) were placed in 4-5 preformed pockets in the parietal peritoneum. At different postoperative intervals (maximum 42 days), a relaparotomy was performed. The regenerated splenic tissue was dissected, weighted and histologically examined. We found a linear correlation between pre- and postoperative weight. However, this correlation applies only to the homogenates with a weight of maximal 200 mg and to the fragments with a weight of maximal 300 mg. We have come to the conclusion that homogenates regenerate better than fragments.

摘要

在一项实验研究中,我们比较了两种在兔子(n = 66)身上制备移植物的方法:将4 - 5片厚度为1毫米、重量递增(5 - 800毫克)的脾组织碎片附着于腹膜上。将重量递增(5 - 800毫克)的脾匀浆置于腹膜壁层的4 - 5个预制袋中。在术后不同时间间隔(最长42天)进行再次剖腹手术。对再生的脾组织进行解剖、称重并进行组织学检查。我们发现术前和术后重量之间存在线性相关性。然而,这种相关性仅适用于最大重量为200毫克的匀浆和最大重量为300毫克的碎片。我们得出结论,匀浆的再生效果优于碎片。

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1
[Transplant conditioning and transplant size in heterotopic autologous spleen transplantation].[异位自体脾移植中的移植预处理与移植大小]
Langenbecks Arch Chir. 1984;362(1):5-16. doi: 10.1007/BF01263315.
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引用本文的文献

1
[Immunologic capacity and blood circulation of splenic autotransplants--experimental results in swine].[脾自体移植的免疫能力与血液循环——猪的实验结果]
Langenbecks Arch Chir. 1986;369:399-403. doi: 10.1007/BF01274398.
2
Alteration of proliferation and subtle changes of protein synthesis in autologous transplanted spleens.自体移植脾脏中增殖的改变及蛋白质合成的细微变化。
Ann Surg. 1989 Nov;210(5):630-6. doi: 10.1097/00000658-198911000-00011.

本文引用的文献

1
Splenic autotransplantation: optimal functional factors.脾自体移植:最佳功能因素
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2
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3
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Chirurg. 1981 Aug;52(8):531-4.
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Chirurg. 1981 Aug;52(8):525-30.
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[Reimplantation of splenic tissue after neonatal abdominal trauma (author's transl)].新生儿腹部创伤后脾组织再植(作者译)
Langenbecks Arch Chir. 1981;354(1):39-43. doi: 10.1007/BF01834015.
6
[Experience with heterotopic autotransplanted splenic tissue in children (author's transl)].儿童异位自体移植脾组织的经验(作者译)
Z Kinderchir. 1982 Apr;35(4):145-52. doi: 10.1055/s-2008-1059925.
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Z Kinderchir. 1982 Mar;35(3):88-9. doi: 10.1055/s-2008-1059909.
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Studies on regeneration of heterotopic splenic autotransplants.异位脾自体移植的再生研究。
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Postsplenectomy sepsis.脾切除术后脓毒症
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The born-again spleen. Return of splenic function after splenectomy for trauma.再生脾脏。创伤性脾切除术后脾功能的恢复
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