阿拉伯儿童的原发性肾病综合征
Primary nephrotic syndrome in Arab children.
作者信息
Elzouki A Y, Amin F, Jaiswal O P
出版信息
Arch Dis Child. 1984 Mar;59(3):253-5. doi: 10.1136/adc.59.3.253.
Abstract
We studied 134 Arab children with primary nephrotic syndrome. The annual incidence was 11.6/100 000 children and the ratio of boys to girls was 1.3:1. Ninety eight per cent were responsive to steroids and the mean age of the children at diagnosis was 5.7 years. On follow up (mean 29.8 months, range 1 month to 11 years) 46% had a frequently relapsing course. Renal biopsy, done in 17 patients with frequently relapsing, steroid-dependent nephrotic syndrome, showed minimal changes in 15 and mesangial proliferative lesions in two. Three of the 129 patients did not respond to steroids; two had focal and segmental sclerosis and the third had mesangial proliferative glomerulonephritis. One patient died.
摘要
我们研究了134名患有原发性肾病综合征的阿拉伯儿童。年发病率为每10万名儿童中有11.6例，男女比例为1.3:1。98%的患儿对类固醇有反应，确诊时患儿的平均年龄为5.7岁。随访（平均29.8个月，范围1个月至11年）发现，46%的患儿病程频繁复发。对17例频繁复发、类固醇依赖型肾病综合征患者进行了肾活检，其中15例显示微小病变，2例显示系膜增生性病变。129例患者中有3例对类固醇无反应；2例患有局灶节段性硬化，第3例患有系膜增生性肾小球肾炎。1例患者死亡。
相似文献
1
Primary nephrotic syndrome in Arab children.阿拉伯儿童的原发性肾病综合征
Arch Dis Child. 1984 Mar;59(3):253-5. doi: 10.1136/adc.59.3.253.
2
Nephrotic syndrome in African children: lack of evidence for 'tropical nephrotic syndrome'?非洲儿童的肾病综合征：“热带肾病综合征”缺乏证据？
Nephrol Dial Transplant. 2006 Mar;21(3):672-6. doi: 10.1093/ndt/gfi297. Epub 2005 Dec 2.
3
[Multicenter study on present status of diagnosis and treatment of steroid-resistant nephrotic syndrome in children].[儿童激素抵抗型肾病综合征诊治现状的多中心研究]
Zhonghua Er Ke Za Zhi. 2014 Jul;52(7):483-7.
4
[Primary nephrotic syndrome. Follow-up of 202 pediatric patients].[原发性肾病综合征。202例儿科患者的随访]
Bol Med Hosp Infant Mex. 1981 May-Jun;38(3):457-72.
5
Nephrotic syndrome in indian children.印度儿童的肾病综合征。
Arch Dis Child. 1975 Aug;50(8):626-30. doi: 10.1136/adc.50.8.626.
6
Cyclosporin A plus prednisone treatment of steroid-sensitive frequently relapsing nephrotic syndrome in children.环孢素A联合泼尼松治疗儿童激素敏感型频繁复发肾病综合征
Turk J Pediatr. 1999 Apr-Jun;41(2):225-30.
7
Steroid-dependent nephrotic syndrome in children: histopathology and relapses after cyclophosphamide treatment.
Kidney Int. 1981 Mar;19(3):454-9. doi: 10.1038/ki.1981.39.
8
Renal biopsy in Saudi children with nephrotic syndrome not responsive to corticosteroid: a preliminary report.沙特患对皮质类固醇无反应的肾病综合征儿童的肾活检：初步报告。
Trop Geogr Med. 1986 Jun;38(2):141-5.
9
The primary nephrotic syndrome in children. Identification of patients with minimal change nephrotic syndrome from initial response to prednisone. A report of the International Study of Kidney Disease in Children.儿童原发性肾病综合征。从对泼尼松的初始反应中识别微小病变型肾病综合征患儿。儿童肾脏病国际研究报告。
J Pediatr. 1981 Apr;98(4):561-4. doi: 10.1016/s0022-3476(81)80760-3.
10
Primary nephrotic syndrome in Arab children in Kuwait.
Pediatr Nephrol. 1989 Apr;3(2):218-20; discussion 221. doi: 10.1007/BF00852914.
引用本文的文献
1
Clinical Characteristics, Pathological Features and Treatment Outcomes of Children With Nephrotic Syndrome at Princess Marina Hospital, Botswana.博茨瓦纳玛丽娜公主医院肾病综合征患儿的临床特征、病理特征及治疗结果
Glob Pediatr Health. 2024 Oct 5;11:2333794X241285272. doi: 10.1177/2333794X241285272. eCollection 2024.
2
Trends in the epidemiology of childhood nephrotic syndrome in Africa: A systematic review.非洲儿童肾病综合征的流行病学趋势：一项系统综述。
Glob Epidemiol. 2021 Aug 25;3:100061. doi: 10.1016/j.gloepi.2021.100061. eCollection 2021 Nov.
3
Estimation of childhood nephrotic syndrome incidence: data from the atlanta metropolitan statistical area and meta-analysis of worldwide cases.儿童肾病综合征发病率的估计：来自亚特兰大都会统计区的数据和全球病例的荟萃分析。
J Nephrol. 2022 Mar;35(2):575-583. doi: 10.1007/s40620-021-01108-9. Epub 2021 Jul 2.
4
Childhood nephrotic syndrome at the University of Abuja Teaching Hospital, Abuja, Nigeria: a preliminary report supports high steroid responsiveness.尼日利亚阿布贾大学教学医院的儿童肾病综合征：一份初步报告支持高类固醇反应性。
Sudan J Paediatr. 2019;19(2):126-139. doi: 10.24911/SJP.106-1547399573.
5
Prospects of genetic testing for steroid-resistant nephrotic syndrome in Nigerian children: a narrative review of challenges and opportunities.尼日利亚儿童类固醇抵抗性肾病综合征基因检测的前景：挑战与机遇的叙述性综述
Int J Nephrol Renovasc Dis. 2019 May 8;12:119-136. doi: 10.2147/IJNRD.S193874. eCollection 2019.
6
Predictive risk factors of steroid dependent nephrotic syndrome in children.儿童激素依赖型肾病综合征的预测风险因素
J Nephropathol. 2017 Jul;6(3):180-186. doi: 10.15171/jnp.2017.31. Epub 2017 Feb 2.
7
Ethnic Differences in Childhood Nephrotic Syndrome.儿童肾病综合征的种族差异
Front Pediatr. 2016 Apr 19;4:39. doi: 10.3389/fped.2016.00039. eCollection 2016.
8
Corticosteroid therapy for nephrotic syndrome in children.儿童肾病综合征的皮质类固醇治疗
Cochrane Database Syst Rev. 2015 Mar 18;2015(3):CD001533. doi: 10.1002/14651858.CD001533.pub5.
9
Epidemiology and predictors of end-stage renal disease in Taiwanese children with idiopathic nephrotic syndrome.台湾特发性肾病综合征儿童终末期肾病的流行病学和预测因素。
J Epidemiol. 2012;22(6):517-22. doi: 10.2188/jea.JE20120033. Epub 2012 Sep 8.
10
Nephrotic syndrome in The Netherlands: a population-based cohort study and a review of the literature.荷兰的肾病综合征：一项基于人群的队列研究和文献复习。
Pediatr Nephrol. 2011 Aug;26(8):1241-6. doi: 10.1007/s00467-011-1851-8. Epub 2011 May 1.
本文引用的文献
1
164 children with nephrosis.164名患有肾病的儿童。
Lancet. 1961 Nov 18;2(7212):1103-10. doi: 10.1016/s0140-6736(61)91026-1.
2
Epidemiology and prevention of kidney disease in Africa.
Trans R Soc Trop Med Hyg. 1980;74(1):8-16. doi: 10.1016/0035-9203(80)90003-6.
3
Steroid-dependent nephrotic syndrome in children: histopathology and relapses after cyclophosphamide treatment.
Kidney Int. 1981 Mar;19(3):454-9. doi: 10.1038/ki.1981.39.
4
Long-term outcome of primary nephrotic syndrome.原发性肾病综合征的长期预后
Arch Dis Child. 1982 Jul;57(7):544-8. doi: 10.1136/adc.57.7.544.
5
Prevalence and pattern of renal disease in eastern Libya.利比亚东部地区肾脏疾病的患病率及模式
Arch Dis Child. 1983 Feb;58(2):106-9. doi: 10.1136/adc.58.2.106.
6
The nephrotic syndrome. Its incidence and implications for the community.肾病综合征。其发病率及对社区的影响。
Am J Dis Child. 1968 Dec;116(6):623-32.
7
Clinicopathological study of nephrotic syndrome in childhood.儿童肾病综合征的临床病理研究
Lancet. 1970 Jun 27;1(7661):1353-9. doi: 10.1016/s0140-6736(70)91268-7.
8
Plasma creatinine and urea concentration in children: normal values for age and sex.儿童血浆肌酐和尿素浓度：按年龄和性别的正常值
J Pediatr. 1976 May;88(5):828-30. doi: 10.1016/s0022-3476(76)81125-0.
9
The nephrotic syndrome in children.
S Afr Med J. 1976 Jan 10;50(2):39-43.
Zotero 插件