Elzouki A Y, Amin F, Jaiswal O P
Arch Dis Child. 1984 Mar;59(3):253-5. doi: 10.1136/adc.59.3.253.
We studied 134 Arab children with primary nephrotic syndrome. The annual incidence was 11.6/100 000 children and the ratio of boys to girls was 1.3:1. Ninety eight per cent were responsive to steroids and the mean age of the children at diagnosis was 5.7 years. On follow up (mean 29.8 months, range 1 month to 11 years) 46% had a frequently relapsing course. Renal biopsy, done in 17 patients with frequently relapsing, steroid-dependent nephrotic syndrome, showed minimal changes in 15 and mesangial proliferative lesions in two. Three of the 129 patients did not respond to steroids; two had focal and segmental sclerosis and the third had mesangial proliferative glomerulonephritis. One patient died.
我们研究了134名患有原发性肾病综合征的阿拉伯儿童。年发病率为每10万名儿童中有11.6例，男女比例为1.3:1。98%的患儿对类固醇有反应，确诊时患儿的平均年龄为5.7岁。随访（平均29.8个月，范围1个月至11年）发现，46%的患儿病程频繁复发。对17例频繁复发、类固醇依赖型肾病综合征患者进行了肾活检，其中15例显示微小病变，2例显示系膜增生性病变。129例患者中有3例对类固醇无反应；2例患有局灶节段性硬化，第3例患有系膜增生性肾小球肾炎。1例患者死亡。
