Hilton R C, Ball J
Ann Rheum Dis. 1984 Apr;43(2):302-7. doi: 10.1136/ard.43.2.302.
The frequency, distribution, and histological characteristics of vertebral rim lesions have been studied at D11 and L4 in 117 post-mortem spines in subjects aged 13-96 years. Only one lesion was found in patients less than 30 years, but thereafter the frequency increased with age. At least one rim was affected in the majority of patients greater than or equal to 50 years. They were found more frequently in the upper than the lower rim and they were also more common anteriorly than posteriorly. Lesions were associated with focal avulsion of the annulus in an otherwise healthy disc or with annular tears running into the rim. Rim lesions can be recognised radiographically by the presence of the vacuum phenomenon, vertebral rim sclerosis with or without a cup-shaped defect in the rim and osteophytes confined to one side of the disc. The histological appearances suggest a traumatic aetiology, and since bone is known to be supplied with pain sensitive nerve endings the lesions may be important in the general context of low back pain.
对117例年龄在13至96岁的受试者的尸体脊柱进行研究，观察了第11胸椎和第4腰椎椎体边缘病变的发生率、分布情况及组织学特征。30岁以下患者仅发现1例病变，但此后发生率随年龄增长而增加。在大多数50岁及以上患者中，至少有一个椎体边缘受到影响。这些病变在上缘比下缘更常见，在前侧也比后侧更常见。病变与健康椎间盘内的纤维环局灶性撕脱或延伸至边缘的纤维环撕裂有关。通过真空现象、椎体边缘硬化（边缘有或无杯状缺损）以及局限于椎间盘一侧的骨赘，可以在影像学上识别边缘病变。组织学表现提示病因与创伤有关，并且由于已知骨骼有对疼痛敏感的神经末梢，这些病变在腰痛的总体背景中可能很重要。
