炎症过程中氧自由基的产生可能受氧浓度限制。
Oxygen-radical production during inflammation may be limited by oxygen concentration.
作者信息
Edwards S W, Hallett M B, Campbell A K
出版信息
Biochem J. 1984 Feb 1;217(3):851-4. doi: 10.1042/bj2170851.
Abstract
The relationship between oxygen-radical production by rat polymorphonuclear leucocytes and O2 concentration was established by the measurement of luminol-dependent chemiluminescence at defined O2 concentrations. The O2 concentration that gave 50% of the maximum stimulated oxygen-radical production was 31 +/- 9 microM for non-opsonized latex beads and 22 +/- 9 microM for chemotactic peptide. The O2 concentration in rheumatoid synovial fluid was approx. 30 microM. It is therefore proposed that radical production at an inflammatory site may be limited by O2 concentration.
摘要
通过在特定氧气浓度下测量鲁米诺依赖的化学发光，确定了大鼠多形核白细胞产生氧自由基与氧气浓度之间的关系。对于未调理的乳胶珠，产生最大刺激氧自由基产量50%时的氧气浓度为31±9微摩尔，对于趋化肽则为22±9微摩尔。类风湿性滑液中的氧气浓度约为30微摩尔。因此，有人提出炎症部位的自由基产生可能受氧气浓度限制。
相似文献
1
Oxygen-radical production during inflammation may be limited by oxygen concentration.炎症过程中氧自由基的产生可能受氧浓度限制。
Biochem J. 1984 Feb 1;217(3):851-4. doi: 10.1042/bj2170851.
2
Two distinct mechanisms for stimulation of oxygen-radical production by polymorphonuclear leucocytes.多形核白细胞产生氧自由基的两种不同机制。
Biochem J. 1983 Nov 15;216(2):459-65. doi: 10.1042/bj2160459.
3
Albumin inhibits human polymorphonuclear leucocyte luminol-dependent chemiluminescence: evidence for oxygen radical scavenging.白蛋白抑制人多形核白细胞鲁米诺依赖性化学发光：氧自由基清除的证据。
Br J Exp Pathol. 1984 Apr;65(2):231-41.
4
Paf-acether generates chemiluminescence in human neutrophils in the absence of cytochalasin B.
Immunopharmacology. 1984 Apr;7(2):135-44. doi: 10.1016/0162-3109(84)90063-8.
5
Measurement of intracellular calcium ions and oxygen radicals in polymorphonuclear leucocyte-erythrocyte 'ghost' hybrids.多形核白细胞-红细胞“空壳”杂交体中细胞内钙离子和氧自由基的测量。
J Physiol. 1983 May;338:537-50. doi: 10.1113/jphysiol.1983.sp014688.
6
Inhibition by adenosine of reactive oxygen metabolite production by human polymorphonuclear leucocytes.腺苷对人多形核白细胞产生活性氧代谢产物的抑制作用。
Biochem J. 1985 Apr 15;227(2):669-74. doi: 10.1042/bj2270669.
7
On radical production by PMA-stimulated neutrophils as monitored by luminol-amplified chemiluminescence.通过鲁米诺增强化学发光监测PMA刺激的中性粒细胞产生自由基的情况。
Free Radic Biol Med. 1991;10(5):305-13. doi: 10.1016/0891-5849(91)90037-4.
8
Mechanism of protection against "reperfusion injury" by aprotinin. Roles of polymorphonuclear leucocytes and oxygen radicals.
Biochem Pharmacol. 1985 May 15;34(10):1757-61. doi: 10.1016/0006-2952(85)90646-x.
9
Oxygen radical production by neutrophils from patients with bacterial infection and rheumatoid arthritis. Measurement of hydrogen peroxide may most accurately represent enhancement of oxygen radical production during infection.细菌感染和类风湿性关节炎患者中性粒细胞产生氧自由基的情况。过氧化氢的测量可能最准确地反映感染期间氧自由基产生的增强。
Inflammation. 1986 Jun;10(2):119-30. doi: 10.1007/BF00915994.
10
Actin polymerization modifies stimulus-oxidase coupling in rat neutrophils.
Biochim Biophys Acta. 1987 Mar 11;927(3):366-71. doi: 10.1016/0167-4889(87)90101-7.
引用本文的文献
1
Metabolism: a potential regulator of neutrophil fate.代谢：中性粒细胞命运的潜在调节因子。
Front Immunol. 2024 Dec 4;15:1500676. doi: 10.3389/fimmu.2024.1500676. eCollection 2024.
2
Normothermia to Decrease Surgical Site Infection Risk: Silver Bullet or Fool's Gold? A Retrospective Cohort Study.常温降低手术部位感染风险：银弹还是愚人金？一项回顾性队列研究。
J Am Acad Orthop Surg Glob Res Rev. 2024 Jun 14;8(6). doi: 10.5435/JAAOSGlobal-D-23-00227. eCollection 2024 Jun 1.
3
Recent Advances of Chitosan-Based Hydrogels for Skin-Wound Dressings.基于壳聚糖的水凝胶用于皮肤伤口敷料的最新进展
Gels. 2024 Feb 29;10(3):175. doi: 10.3390/gels10030175.
4
Perioperative Hypothermia-A Narrative Review.围手术期低体温——一篇叙述性综述。
Int J Environ Res Public Health. 2021 Aug 19;18(16):8749. doi: 10.3390/ijerph18168749.
5
F0F1 ATP synthase regulates extracellular calcium influx in human neutrophils by interacting with Ca2.3 and modulates neutrophil accumulation in the lipopolysaccharide-challenged lung.F0F1 ATP 合酶通过与 Ca2.3 相互作用调节人中性粒细胞细胞外钙内流，并调节脂多糖刺激的肺中中性粒细胞的聚集。
Cell Commun Signal. 2020 Feb 4;18(1):19. doi: 10.1186/s12964-020-0515-3.
6
Fluorinated Methacrylamide Chitosan Hydrogel Dressings Improve Regenerated Wound Tissue Quality in Diabetic Wound Healing.氟化甲基丙烯酰胺壳聚糖水凝胶敷料改善糖尿病伤口愈合中再生伤口组织质量
Adv Wound Care (New Rochelle). 2019 Aug 1;8(8):374-385. doi: 10.1089/wound.2018.0887. Epub 2019 Jul 25.
7
Oxygen Regulation in Development: Lessons from Embryogenesis towards Tissue Engineering.发育中的氧调节：从胚胎发生到组织工程的启示。
Cells Tissues Organs. 2018;205(5-6):350-371. doi: 10.1159/000493162. Epub 2018 Oct 1.
8
Negative Pressure Wound Therapy on Closed Surgical Wounds With Dead Space: Animal Study Using a Swine Model.负压伤口治疗对伴有死腔的闭合性手术伤口的影响：使用猪模型的动物研究
Ann Plast Surg. 2016 Jun;76(6):717-22. doi: 10.1097/SAP.0000000000000231.
9
Effect of stress-induced reversible ischemia on serum concentrations of ischemia-modified albumin, natriuretic peptides and placental growth factor.应激诱导的可逆性缺血对缺血修饰白蛋白、利钠肽和胎盘生长因子血清浓度的影响。
Clin Res Cardiol. 2007 Mar;96(3):152-9. doi: 10.1007/s00392-007-0469-5. Epub 2006 Dec 22.
10
Glucose- and phorbol myristate acetate-stimulated oxygen consumption and superoxide production in rat peritoneal macrophages is inhibited by dexamethasone.地塞米松可抑制葡萄糖和佛波酯刺激的大鼠腹腔巨噬细胞的氧消耗和超氧化物生成。
Biochem J. 1993 Apr 15;291 ( Pt 2)(Pt 2):509-14. doi: 10.1042/bj2910509.
本文引用的文献
1
2
A membrane-covered photobacterium probe for oxygen measurements in the nanomolar range.
Anal Biochem. 1981 Sep 1;116(1):17-21. doi: 10.1016/0003-2697(81)90315-8.
3
The association of FAD with the cytochrome b-245 of human neutrophils.黄素腺嘌呤二核苷酸（FAD）与人类中性粒细胞细胞色素b - 245的关联。
Biochem J. 1982 Dec 15;208(3):759-63. doi: 10.1042/bj2080759.
4
Decrease in apparent Km for oxygen after stimulation of respiration of rat polymorphonuclear leukocytes.大鼠多形核白细胞呼吸受刺激后氧的表观米氏常数降低。
FEBS Lett. 1983 Sep 5;161(1):60-4. doi: 10.1016/0014-5793(83)80730-3.
5
Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog.通过去除犬体内的中性粒细胞来减轻缺血性心肌损伤的程度。
Circulation. 1983 May;67(5):1016-23. doi: 10.1161/01.cir.67.5.1016.
6
Oxygen affinities of the hydrogenosome-containing protozoa Tritrichomonas foetus and Dasytricha ruminantium, and two aerobic protozoa, determined by bacterial bioluminescence.通过细菌生物发光法测定含氢化酶体的原生动物胎儿三毛滴虫和反刍兽三毛滴虫以及两种需氧原生动物的氧亲和力。
J Gen Microbiol. 1982 May;128(5):1019-22. doi: 10.1099/00221287-128-5-1019.
7
Two distinct mechanisms for stimulation of oxygen-radical production by polymorphonuclear leucocytes.多形核白细胞产生氧自由基的两种不同机制。
Biochem J. 1983 Nov 15;216(2):459-65. doi: 10.1042/bj2160459.
8
Delineation of the catalytic components of the NADPH-dependent O2- generating oxidoreductase of human neutrophils.
Biochem Biophys Res Commun. 1983 Feb 10;110(3):873-9. doi: 10.1016/0006-291x(83)91042-2.
9
Role of myeloperoxidase in luminol-dependent chemiluminescence of polymorphonuclear leukocytes.髓过氧化物酶在多形核白细胞鲁米诺依赖性化学发光中的作用
Infect Immun. 1983 Feb;39(2):736-41. doi: 10.1128/iai.39.2.736-741.1983.
10
Production of superoxide, hydrogen peroxide and hydroxyl radicals by phagocytic cells: a cause of chronic inflammatory disease?吞噬细胞产生超氧化物、过氧化氢和羟基自由基：慢性炎症性疾病的一个病因？
Cell Biol Int Rep. 1982 Jun;6(6):529-42. doi: 10.1016/0309-1651(82)90175-8.
Zotero 插件