Farrands P A, Hardcastle J D
Gut. 1984 May;25(5):445-7. doi: 10.1136/gut.25.5.445.
The prevalence and significance of colorectal symptoms within a group of 1533 individuals was assessed using a self-completion questionnaire and results compared with faecal occult blood screening. One hundred and twenty eight individuals listed one or more symptoms, while only 12 had a positive blood occult test. Of the subjects studied, 6.6% had noticed bleeding from the rectum in the last six months, 8.7% diarrhoea, and 12.3% a change in bowel habit. Examination of these individuals revealed one (0.8%) to have an adenoma of the colon. By comparison, occult blood testing identified two patients with carcinoma and four with adenoma. Both of the patients with carcinoma and three out of the four with adenoma had replied negative to the questionnaire suggesting the self-completion questionnaire to be of little value in the early detection of colorectal neoplasia.
通过一份自填式问卷评估了1533名个体中结直肠症状的患病率及意义,并将结果与粪便潜血筛查结果进行比较。128人列出了一种或多种症状,而只有12人粪便潜血检测呈阳性。在研究对象中,6.6%的人在过去六个月内注意到直肠出血,8.7%有腹泻,12.3%有排便习惯改变。对这些个体的检查发现1人(0.8%)患有结肠腺瘤。相比之下,潜血检测发现2例癌症患者和4例腺瘤患者。两名癌症患者以及四名腺瘤患者中的三名对问卷的回答为阴性,这表明自填式问卷在结直肠肿瘤的早期检测中价值不大。