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大蒜、姜黄和阿魏对小鼠的遗传毒性。

Genotoxicity of garlic, turmeric and asafoetida in mice.

作者信息

Abraham S K, Kesavan P C

出版信息

Mutat Res. 1984 Apr;136(1):85-8. doi: 10.1016/0165-1218(84)90138-1.

DOI:10.1016/0165-1218(84)90138-1
PMID:6717474
Abstract

The genotoxic effects of orally administered garlic and turmeric were evaluated in bone-marrow cells of mice by performing the micronucleus test. Another spice, asafoetida, was tested for the induction of sister-chromatid exchanges (SCEs) in spermatogonia of mice. Results of the micronucleus test with garlic and turmeric were not significantly different from control values. Orally administered asafoetida, however, showed a weak SCE-inducing effect in spermatogonia.

摘要

通过进行微核试验,评估了口服大蒜和姜黄对小鼠骨髓细胞的遗传毒性作用。对另一种香料阿魏进行了测试,以检测其对小鼠精原细胞姐妹染色单体交换(SCE)的诱导作用。大蒜和姜黄的微核试验结果与对照值无显著差异。然而,口服阿魏对精原细胞显示出较弱的SCE诱导作用。

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