患有和未患肺气肿患者肺部上叶和下叶的气道疾病。
Airway disease in upper and lower lobes in lungs of patients with and without emphysema.
作者信息
Wright J L, Wiggs B J, Hogg J C
出版信息
Thorax. 1984 Apr;39(4):282-5. doi: 10.1136/thx.39.4.282.
Abstract
To determine whether pathological changes in the small airways are evenly distributed throughout the lung and whether there is an association of small airway disease with emphysema, pathological abnormalities of the small airways were graded in the upper and lower lobes of 13 surgical lung specimens. Except for slightly increased degrees of respiratory bronchiolar inflammation in the lower lobe, no differences were found between the two sites, nor was there any relationship between the presence of pathological abnormalities in the small airways and the presence of centrilobular emphysema. It is concluded that the predilection of centrilobular emphysema for the upper lung zone is not associated with a difference in intensity of airway disease between upper and lower lobes.
摘要
为了确定小气道的病理变化在整个肺内是否均匀分布，以及小气道疾病与肺气肿之间是否存在关联，我们对13个手术切除的肺标本的上叶和下叶小气道的病理异常进行了分级。除下叶呼吸性细支气管炎症程度略有增加外，两个部位未发现差异，小气道病理异常的存在与小叶中心型肺气肿的存在之间也没有任何关系。得出的结论是，小叶中心型肺气肿对上肺区的偏好与上叶和下叶气道疾病强度的差异无关。
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