Soerjadi-Liem A S, Snoeyenbos G H, Weinack O M
Avian Dis. 1984 Jan-Mar;28(1):139-46.
Resistance of young chicks to Campylobacter fetus subsp. jejuni was substantially increased by early exposure to native gut microflora. Protection was demonstrated against two human isolates and a chicken isolate of C. fetus subsp. jejuni. Significant protection against the chicken isolate was observed throughout a 91-day test period. Infection reached 100% (25/25) in the untreated group at 56 days of age and only 4% (1/25) in the group treated with native gut microflora. Campylobacter fetus subsp. jejuni was isolated from the ceca and less frequently from the gall bladder and liver of chicks that actively shed the bacteria. Cultures of feces from chicks reared on wood-shavings litter were often negative, suggesting that culturing litter as an indicator of infection has limited value.
雏鸡早期接触天然肠道微生物群可显著增强其对空肠弯曲菌胎儿亚种的抵抗力。已证明对两株人源分离株和一株空肠弯曲菌胎儿亚种鸡源分离株具有保护作用。在整个91天的试验期内，观察到对鸡源分离株有显著保护作用。在56日龄时，未处理组的感染率达到100%（25/25），而用天然肠道微生物群处理的组仅为4%（1/25）。从积极排出该细菌的雏鸡的盲肠中分离出空肠弯曲菌胎儿亚种，从胆囊和肝脏中分离出的频率较低。在刨花垫料上饲养的雏鸡粪便培养物通常为阴性，这表明将垫料培养作为感染指标的价值有限。
