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空肠弯曲杆菌胎儿亚种在雏鸡中的肠道定植与竞争排斥

Intestinal colonization and competitive exclusion of Campylobacter fetus subsp. jejuni in young chicks.

作者信息

Soerjadi A S, Snoeyenbos G H, Weinack O M

出版信息

Avian Dis. 1982 Jul-Sep;26(3):520-4.

PMID:7150145
Abstract

Colonization of Campylobacter fetus subsp. jejuni was investigated in monoxenic and holoxenic chicks. In monoxenic chicks, major colonization was found in the crop and ceca, with populations in the ceca consistently reaching 10(9) colony-forming-units/ml of cecal contents over the 28-day test period. Bacteremia was found in most chicks, but no significant gross pathological lesions were detected. In holoxenic chicks, major colonization occurred only in the ceca, and no evidence of bacteremia was detected. Colonization by native gut microflora sharply reduced subsequent colonization by C. fetus subsp. jejuni. The protective mechanism is perhaps the same as that protective against paratyphoid salmonellae and pathogenic strains of Escherichia coli.

摘要

对空肠弯曲杆菌胎儿亚种在单菌和全菌雏鸡中的定植情况进行了研究。在单菌雏鸡中,主要定植部位是嗉囊和盲肠,在28天的试验期内,盲肠中的菌量始终达到每毫升盲肠内容物10⁹个菌落形成单位。大多数雏鸡出现菌血症,但未检测到明显的大体病理损伤。在全菌雏鸡中,主要定植仅发生在盲肠,未检测到菌血症迹象。原生肠道微生物群的定植显著减少了随后空肠弯曲杆菌胎儿亚种的定植。其保护机制可能与针对副伤寒沙门氏菌和致病性大肠杆菌菌株的保护机制相同。

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