Warren E W, Groome D H
Br J Psychiatry. 1984 Apr;144:370-5. doi: 10.1192/bjp.144.4.370.
Thirty-eight patients suffering from severe depression were given a course of ECT (Electroconvulsive therapy) in one of three waveforms. These were high-energy sine wave (HS), high-energy pulse (HP), and low-energy pulse (LP). Patients were assigned to one of these treatments on a double-blind basis. The patients were given a battery of memory tests before ECT commenced, after three treatments, at the termination of treatment, and two weeks after the last treatment. The marked improvement in both verbal and nonverbal memory scores was attributed to the lifting of depression. No significant differences were found between the memory scores of the three treatment groups at any point during the treatment period.
38名重度抑郁症患者接受了一个疗程的电休克疗法（ECT），采用三种波形之一进行治疗。这三种波形分别是高能正弦波（HS）、高能脉冲波（HP）和低能脉冲波（LP）。患者通过双盲方式被分配到其中一种治疗组。在ECT开始前、三次治疗后、治疗结束时以及最后一次治疗后两周，对患者进行了一系列记忆测试。言语和非言语记忆分数的显著改善归因于抑郁症的缓解。在治疗期间的任何时间点，三个治疗组的记忆分数之间均未发现显著差异。
