De Muylder X, Lord J
Can Med Assoc J. 1984 May 15;130(10):1296-301.
Antispermatozoal antibodies in the woman, the man, or both, may be the cause of nonorganic infertility in a small number of couples. The antibodies are most often found in the serum or in the genital fluids. Diagnosis is based on the postcoital test and on various laboratory tests to assess sperm-cervical mucous compatibility and to detect antispermatozoal antibodies. In women the strongest relation between results of laboratory tests and infertility is between the presence of serum antispermatozoal antibodies and infertility of more than 3 years' duration. In men there is a relation between high levels of these antibodies in the semen and infertility. Various treatments have been proposed, but further prospective studies are needed. However, promising results have been reported with homologous intrauterine insemination and with immunosuppression in men.
女性、男性或双方体内的抗精子抗体可能是少数夫妇非器质性不孕的原因。这些抗体最常见于血清或生殖液中。诊断基于性交后试验以及各种实验室检测，以评估精子与宫颈黏液的相容性并检测抗精子抗体。在女性中，实验室检测结果与不孕之间最密切的关系存在于血清抗精子抗体的存在与持续超过3年的不孕之间。在男性中，精液中这些抗体的高水平与不孕有关。已经提出了各种治疗方法，但还需要进一步的前瞻性研究。然而，据报道，同源宫内人工授精和男性免疫抑制取得了有希望的结果。
