Fellows I W, MacDonald I A, Bennett T
Clin Sci (Lond). 1984 Jun;66(6):733-9. doi: 10.1042/cs0660733.
Ten healthy male subjects ingested ethanol (BP; 0.5 g/kg body weight) after an overnight fast, on two separate occasions, at environmental temperatures of either 21 degrees C or 30 degrees C. The mean maximal fall in deep body temperature was not significantly different on the two occasions, being 0.18 degrees C and 0.17 degrees C respectively. Metabolic rates throughout the experiments at the two temperatures were not significantly different. The vasodilatation of the hand and forearm vascular beds after ethanol ingestion was markedly reduced at the lower environmental temperature. In three subjects who ingested a higher dose of ethanol (BP; 1.0 g/kg body weight) after an overnight fast, at an environmental temperature of 21 degrees C, the mean maximum fall in core temperature was 0.15 degrees C, which was not significantly different from the change seen after consumption of the lower dose of ethanol. It is likely that the failure of ethanol ingestion to provoke hypothermia at the lower environmental temperature was due to the attenuated vasodilatation observed under these conditions.
十名健康男性受试者在禁食过夜后，于环境温度分别为21摄氏度或30摄氏度的两个不同场合摄入乙醇（BP；0.5克/千克体重）。两次的深部体温平均最大降幅无显著差异，分别为0.18摄氏度和0.17摄氏度。在这两个温度下，整个实验过程中的代谢率无显著差异。在较低环境温度下，摄入乙醇后手部和前臂血管床的血管舒张明显减弱。在三名禁食过夜后于21摄氏度环境温度下摄入较高剂量乙醇（BP；1.0克/千克体重）的受试者中，核心温度的平均最大降幅为0.15摄氏度，这与摄入较低剂量乙醇后观察到的变化无显著差异。在较低环境温度下，摄入乙醇未能引发体温过低，可能是由于在这些条件下观察到的血管舒张减弱。
