Lubin J H, Blot W J, Berrino F, Flamant R, Gillis C R, Kunze M, Schmahl D, Visco G
Int J Cancer. 1984 May 15;33(5):569-76. doi: 10.1002/ijc.2910330504.
A case-control study of lung cancer involving interviews with 7,804 cases and 15,207 hospital-based controls was carried out in seven locations in Western Europe. The large study size permitted the calculation of precise estimates of the relative risk of lung cancer associated with smoking different types of cigarettes. Lifelong nonfilter smokers were at nearly twice the risk of lung cancer compared to lifelong filter smokers after controlling for duration of cigarette use and number smoked per day (RR = 1.7 for males and 2.0 for females). Lung cancer risks for filter, nonfilter and mixed smokers increased in proportion to intensity and duration of smoking and decreased with years since stopping smoking. The findings indicate that prevention activities should continue to emphasize smoking cessation, although switching to low-tar cigarettes may also yield some reductions in lung cancer risk.
在西欧的七个地点开展了一项肺癌病例对照研究，对7804例病例和15207名医院对照进行了访谈。这项大规模研究能够精确计算出与吸食不同类型香烟相关的肺癌相对风险。在控制了吸烟时长和每日吸烟量后，终身不吸过滤嘴香烟者患肺癌的风险几乎是终身吸过滤嘴香烟者的两倍（男性相对风险为1.7，女性为2.0）。过滤嘴香烟吸烟者、非过滤嘴香烟吸烟者和混合型香烟吸烟者患肺癌的风险随着吸烟强度和时长的增加而上升，并随着戒烟时间的延长而降低。研究结果表明，预防活动应继续强调戒烟，不过改用低焦油香烟或许也能在一定程度上降低患肺癌的风险。
