利用光在体内对DNA进行足迹分析。
Use of light for footprinting DNA in vivo.
作者信息
Becker M M, Wang J C
出版信息
Nature. 1984;309(5970):682-7. doi: 10.1038/309682a0.
DOI:10.1038/309682a0
PMID:6728031
Abstract
A new ' photofootprinting ' technique, which uses light to detect protein-DNA contacts as well as changes in the structure of DNA at the base pair level, has been developed and used to detect contacts between lac repressor and the lac operator in Escherichia coli cells.
摘要
一种新的“光足迹法”技术已经被开发出来，该技术利用光来检测蛋白质与DNA的相互作用以及碱基对水平上DNA结构的变化，并已用于检测大肠杆菌细胞中乳糖阻遏物与乳糖操纵基因之间的相互作用。
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