Franks N P, Lieb W R
Nature. 1978 Jul 27;274(5669):339-42. doi: 10.1038/274339a0.
General anaesthetics were found to have no effect on lipid bilayer structures when studied using X-ray and neutron diffraction. Combined gaseous and aqueous phase solubility data suggested that the primary site of action of general anaesthetics has both polar and nonpolar characteristics, and probably involves protein.
当使用X射线和中子衍射进行研究时，发现全身麻醉剂对脂质双层结构没有影响。气相和水相溶解度数据综合表明，全身麻醉剂的主要作用位点具有极性和非极性特征，可能涉及蛋白质。
