Gunion M W, Grijalva C V, Tache Y, Novin D
Brain Res. 1984 May 14;299(2):239-46. doi: 10.1016/0006-8993(84)90705-4.
The peptide bombesin-14 causes hyperglycemia when injected into the cisterna magna of rats. We report that acute lateral hypothalamic lesions block bombesin hyperglycemia. Lateral thalamic lesions do not have this effect. We further report that transections on the lateral or posterior borders of the lateral hypothalamus also block bombesin hyperglycemia. Cuts on the medial border also somewhat diminish this hyperglycemia, while cuts on the anterior border are not reliably effective. These results suggest that fibers traversing the lateral hypothalamus are involved in the hyperglycemic response to intracisternal bombesin-14.
将肽类物质铃蟾肽 - 14注入大鼠脑池时会导致高血糖。我们报告急性下丘脑外侧损伤可阻断铃蟾肽引起的高血糖。丘脑外侧损伤则无此作用。我们进一步报告，下丘脑外侧外侧或后部边界的横断也可阻断铃蟾肽引起的高血糖。内侧边界的切断也会在一定程度上减轻这种高血糖，而在前部边界的切断则效果不太可靠。这些结果表明，穿过下丘脑外侧的纤维参与了对脑池内注射铃蟾肽 - 14的高血糖反应。
